Gastro: Virulence Flashcards

1
Q

Staph. aureus

A

Heat stable enterotoxin

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2
Q

Bacillus cereus; emetic

A

Cereulide peptide

Heat stable toxin

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3
Q

Bacillus cereus; diarrhoeal

A

Haemolysin

Heat labile enterotoxin

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4
Q

Clostridium perfringens

A

Heat labile enterotoxin

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5
Q

Vibrio cholerae

A

Colonisation:
• Tcp
Toxin:
• Cholera toxin

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6
Q

EHEC

A
Colonisation:
• Tir + Intimin
• Type III SS
Toxin:
• Shiga toxin
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7
Q

ETEC

A
Colonisation:
• CFA
Toxin:
• ST
• LT
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8
Q

EPEC

A

Colonisation:
• Bfp
Toxin:
• none

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9
Q

Shigella

A
Colonisation:
• Type III SS
• Ipa
• IcsA
Toxin:
• Shiga toxin
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10
Q

Salmonella

A
Colonisation:
• Sip
• Type III SS
Toxin:
• Ssa
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11
Q

Campylobacter

A

Colonisation:
• ?
Toxin:
• ? Cytolytic endotoxin

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12
Q

Yersinia enterocolytica

A
Colonisation:
• Type III SS
• Yop
Toxin:
• Yop
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13
Q

Vibrio parahaemolyticus

A

Colonisation:
• ?
Toxin:
• ? no toxin

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14
Q

Giardia lamblia

A

Colonisation:
• ventral sucking disc
Toxin:
• none

Virulence:
• malabsorption due to colonisation

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15
Q

Entamoeba histolytica

A

Colonisation:
• digalatose + surface lectin
Toxin:
• preformed toxin (forms pores)

Virulence:
toxin forms pores

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16
Q

Cryptosporidium

A

Colonisation:
• glycoproteins + lectins
Toxin:
• ?

17
Q

Rotavirus

A

Colonisation:
• outer capsid protein spikes
Toxin:
• enterotoxin

Virulence:
• villus blunting

18
Q

Norovirus

A

Colonisation:
• histo blood group antigens
Toxin:
• ?

Virulence
• villus blunting