Gastro

Question 1

Chron’s micro features

Answer 1

Transmural

Granulommatous

Question 2

When does Chron’s get diagnosed

Answer 2

15-30
or
50-70

Question 3

Chron’s smoking risk?

Answer 3

3-4x

Question 4

How long before diarrhoea is called chronic?

Answer 4

6 weeks

Question 5

Abdominal symptoms of Chrons?

Answer 5

Abdo pain

bloody chronic diarrhoea

Question 6

Systemic symptoms of Chrons?

Answer 6

Weight loss
Malaise
Anorexia
Fever

Question 7

Other parts of the body affected by Chrons

Answer 7

Eyes
Mouth
Skin
Joints
Perianal

Question 8

Perianal lesions with chronic diarrhoea is suggestive of what condition?

Answer 8

Chron’s

Question 9

Gold standard for investigation for Chron’s

Answer 9

Ileocolonoscopy with biopsy

Question 10

What bloods for chron’s

Answer 10

All the ones with abbreviations:
FBC, CRP, U+E, LFT
Also stool culture and microscopy

Question 11

Patient with suspected Chron’s would be admitted if what symptoms?

Answer 11

Severe abdo pain
Severe diarrhoea (>8 per day)
Bowel obstruction
Fever and systemically unwell

Question 12

What is severe diarrhoea defined as?

Answer 12

> 8 times per day

Question 13

First line treatment for Chron’s?

Answer 13

Monotherapy with glucocorticoid:
pred
methyl pred
IV hydrocortisone

Question 14

Name a biologic drug used in Chron’s

Answer 14

infliximab

adalimumab

Question 15

What useful drug can’t be used during Chron’s flare

Answer 15

Loperamide
(and other antidiarrhoeals)
This can result in toxic megacolon

Question 16

Name an add on drug for treatment of steroid resistant chron’s

Answer 16

Methotrexate

Azathioprine

Question 17

Name 1 lifestyle intervention for Chron’s

Answer 17

Smoking cessation