Gastritis Flashcards

1
Q

What is gastritis

A

Inflammation of the gastric mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Types of gastritis

A

Acute - associated with neutrophilic infiltration

Chronic - associated with mononuclear cells (lymphocytes, plasma cells and macrophages)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clinical presentation of gastritis

A
Usually asymptomatic
Sometimes functional dyspepsia (indigestion)
Upper abdominal pain
Nausea and vomiting
(Autoimmune pernicious anaemia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pathophysiology of gastritis

A

Local inflammatory response to infection by H.pylori

Can cause an increase in gastric acid secretion through presence of H.pylori, also causing further inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Aetiology of gastritis

A

Most commonly: H. pylori infection.
Also possible; autoimmune gastritis (antibodies to parietal cells and intrinsic factor), viruses, duodeno-gastric reflux.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Diagnosis of gastritis

A

Endoscopy: Can appear reddened, or normal.
Histological change; detected through biopsy.
Blood tests, stool tests.
Inflammation or erosions.
Faecal occult blood test, faecal calprotecin (intestinal), stool culture.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Treatment of gastritis

A

Eradication of H. pylori (triple therapy: clarithromycin, omeprazole, metronidazole)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Complications of gastritis

A
Peptic ulcer
Pernicious anaemia (if due to AI attack of IF)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a gastropathy

A

Injury to the gastric mucosa with epithelial cell damage and regeneration.
Little to no inflammation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Clinical presentation of gastropathy

A

Indigestion
Vomiting
Haemorrhage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pathophysiology of gastropathy

A

Reduction in protective prostaglandins by NSAIDs use, causes the acidic contents of the stomach/duodenum to break down the mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Aetiology of gastropathy

A

Most commonly: Use of NSAIDs.

Also possible; severe stress, high amounts of alcohol, CMV and Herpes simplex infection.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Diagnosis of gastropathy

A

Endoscopy: Erosions and sub epithelial haemorrhage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Treatment of gastropathy

A

PPI with removal of causative agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Complication of gastropathy

A

Peptic ulcer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe triple therapy treatment of Gastritis or Peptic Ulcer

A

Clarithromycin
Omeprazole
Metronidazole or Amoxicillin