Gastric Motility and Secretions

Question 1

Describe the receptive relaxation reflex

Answer 1

Part of the storing phase.
Initiated by swallowing causing the vagus nerve to relax the stomach in anticipation of food.

*Non cholinergic, non adernergic.

Question 2

Describe Gastric Accomodation

Answer 2

The second part of the storing phase, the stomach enlarges even more following reception of food!
Fundus is mostly dilating under ENS and Vagus control.

Question 3

What effect does Secretin have on the stomach and what initiates its response?

Answer 3

Released in response to HCL in the duodenum, it serves to impair gastric emptying.

Question 4

What effect does CCK have on the stomach and what stimulates its response?

Answer 4

CCK is stimulated by fat content in the duodenum. It serves to slow gastric emptying by use of NO.

Question 5

What effect does Gastrin have on the stomach and what stimulates its action?

Answer 5

Gastrin is stimulated by protein in the stomach!

Causes the stomach to slow emptying by use of 5HT and VIP.

Question 6

What stimulates ENS activity in the stomach to delay gastric emptying?

Answer 6

Duodenal distention!

Question 7

What are the key neurotransmitters in the emetic response?

Answer 7

Acetylcholine
Histamine
Serotonin
Dopamine

Question 8

What are the two emetic zones that recieve emetic information?

Answer 8

The Chemoreceptor trigger zone
and
The emetic center!

Question 9

What is Gastroparesis?

Answer 9

Impaired motility of the stomach associated with impairements in the pyloric region or pyloric sphincter.

Can be related to diabeties or infantile pyloric stenosis.