Fluid and Electrolytes

Question 1

What are the four key transport proteins for sodium?

Answer 1

SGLT1 in duodenum

Amino acid sodium transporter B in jejunum

Na/H+ interdigestive transporter in jejunum

Na open channel in Colon.

Question 2

What maintains the sodium concentration gradient in the large and small intestine?

Answer 2

The sodium potassium basolateral ATPase.

Question 3

Where is potassium secreted in the intestines?

Answer 3

Secreted by the large intestines.

Question 4

What steps occur to cause mass secretion of electrolytes?

Answer 4

Sodium channels are inhibited while the CFTR channels are activated.

Question 5

What are some drugs that can cause mass secretion of electrolytes?

Answer 5

Glucocorticosteroids and other Steroids.

Question 6

What effect do prostaglandins and histamine have on electrolytes?

Answer 6

Cause electrolyte secretion by upregulating CFTR and inhibiting NA/H exchanger.

Question 7

Which neurotransmitters cause a net secretion?

Answer 7

Ach
Serotonin
VIP

Question 8

Which neurotransmitters cause fluid absorption

Answer 8

Somatostatin.