Blood Flashcards
In what cases would the Anion gap increase?
The anion gap would increase in cases of hypoalbuminemia. the body creates more bicarb.
In what cases would the anion gap decrease?
Metabolic acidosis in which more bicarb ions would be used up.
What is the formula for the anion gap?
AG = Na + (Cl + HCO3-)
What does Haptoglobulin do?
Carries free hemoglobin that has been released from ruptured rbc back to the liver for recycle.
If the body runs out of haptoglobulin what occurs?
The patient is at risk for hemolytic anemia.
Increased Lactate dehydrogenase in the blood is a marker for what?
A marker for mass blood cell hemolysis.
How can Erythropoiesis be measured?
immature RBC are released into the blood stream and require 24-48 hours before they are functional.
This can be measured for erythroporesis.
What sort of disease would cause erythropoieten levels to remain high regardless of blood concentration?
Diseases that are blocking intake of air.
If there are low reticulocytes and high concentrations of erythropoieten this means….
Primary defect in the maturing process of RBC.
What is hematocrit?
Total ammount of RBC divided by the total blood volume.
What is the mean corpuscular volume?
Single red blood cell volume.
What is the mean corpuscular hemoglobin?
The average amount of hemoglobin in an average RBC.
What is the mean corpuscular hemoglobin concentration?
Average hemoglobin concentration in a given volume of RBC.
Increased levels of urobillogen in the urine is a sign of what?
A sign of hemolytic diseases.
Rapidly dropping haptoglobin levels would be a sign of what?
A sign of a hemolytic disease, this is because once haptogobulin binds hemoglobin it has a very short half life (72 hours).
An MCV level
Microcytic anemia
An MCV between 80 and 100 would be indicative of what type of anemia?
Normal MCHC
Normocytic anemia
Usually has a normal MCHC
An MCV > 100 fL would indicate what?
Variable MCHC
Would indicate macrocytic anemia as seen in folic acid and vitamin B12 deficiencies.
What effect does thrombopoietin (TPO) have?
Released from the liver and bone marrow which Induces the formation of immature megakaryocytes
