Blood Flashcards

1
Q

In what cases would the Anion gap increase?

A

The anion gap would increase in cases of hypoalbuminemia. the body creates more bicarb.

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2
Q

In what cases would the anion gap decrease?

A

Metabolic acidosis in which more bicarb ions would be used up.

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3
Q

What is the formula for the anion gap?

A

AG = Na + (Cl + HCO3-)

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4
Q

What does Haptoglobulin do?

A

Carries free hemoglobin that has been released from ruptured rbc back to the liver for recycle.

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5
Q

If the body runs out of haptoglobulin what occurs?

A

The patient is at risk for hemolytic anemia.

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6
Q

Increased Lactate dehydrogenase in the blood is a marker for what?

A

A marker for mass blood cell hemolysis.

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7
Q

How can Erythropoiesis be measured?

A

immature RBC are released into the blood stream and require 24-48 hours before they are functional.
This can be measured for erythroporesis.

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8
Q

What sort of disease would cause erythropoieten levels to remain high regardless of blood concentration?

A

Diseases that are blocking intake of air.

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9
Q

If there are low reticulocytes and high concentrations of erythropoieten this means….

A

Primary defect in the maturing process of RBC.

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10
Q

What is hematocrit?

A

Total ammount of RBC divided by the total blood volume.

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11
Q

What is the mean corpuscular volume?

A

Single red blood cell volume.

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12
Q

What is the mean corpuscular hemoglobin?

A

The average amount of hemoglobin in an average RBC.

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13
Q

What is the mean corpuscular hemoglobin concentration?

A

Average hemoglobin concentration in a given volume of RBC.

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14
Q

Increased levels of urobillogen in the urine is a sign of what?

A

A sign of hemolytic diseases.

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15
Q

Rapidly dropping haptoglobin levels would be a sign of what?

A

A sign of a hemolytic disease, this is because once haptogobulin binds hemoglobin it has a very short half life (72 hours).

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16
Q

An MCV level

A

Microcytic anemia

17
Q

An MCV between 80 and 100 would be indicative of what type of anemia?

Normal MCHC

A

Normocytic anemia

Usually has a normal MCHC

18
Q

An MCV > 100 fL would indicate what?

Variable MCHC

A

Would indicate macrocytic anemia as seen in folic acid and vitamin B12 deficiencies.

19
Q

What effect does thrombopoietin (TPO) have?

A

Released from the liver and bone marrow which Induces the formation of immature megakaryocytes