Gallbladder Disorders/Pancreatic Disorders Flashcards

1
Q

Female, Fat, Fertile (pregnant) Forty are risk factors for?

A

Gallstones

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2
Q

Gallstones are divided into?

A

Cholesterol and Pigmented

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3
Q

Cholesterol stone is MC in the?

A

West

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4
Q

Jaundice Fever and RUQ?

A

Cholangitis

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5
Q

Cholesterol stone is radiolucent or opaque?

A

Cholesterol stone is radiolucent

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6
Q

Pigmented stone is radiolucent or opaque?

A

Opaque

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7
Q

Causes of Cholesterol stones?

A

Crohns=>destroys terminal ileum, decreased bile acid=>increased cholesterol stones

Estrogen=>Increased HMG-CoA and Increased LDL receptors

Cholestyramine=>decreased bile acids=>increased cholesterol

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8
Q

Cholecystitis MCC?

A

blocking the cystic duct=>infection

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9
Q

inspiratory arrest on RUQ palpation due to pain is seen in?

A

Cholecystitis

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10
Q

RUQ pain that radiates to the R. Scapula?

A

Acute Cholecystitis

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11
Q

Rokitanksy-Aschoff sinus formation and vague RUQ?

A

Chronic Cholecystitis

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12
Q

Cholecystitis can lead to _______ which leads to_______?

A

porcelain gallbladder (calcified gallbaldder)=>Gallbladder carcinoma

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13
Q

Acute pancreatitis MCC?

A

Alcohol and Gallstones

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14
Q

Acute pancreatitis presentation?

A

epigastric abdominal pain radiating to back

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15
Q

Acute pancreatitis labs?

A

Lipase (higher specificity)

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16
Q

First enzyme to be activated is?

A

Trypsin

17
Q

Complication of acute pancreatitis?

A

Pseudocyst

18
Q

Chronic pancreatitis MC adult? MC child?

A

Adult=>alcohol

child=>CF

19
Q

Chronic Pancreatitis leads to?

A

Pancreatic insufficiency=>steatorrhea, fat soluble vitamin

20
Q

Pancreatic adenocarcinoma are most common in?

A

pancreatic head (head of pancreas)

21
Q

Pancreatic cancer marker?

A

CA 19-9 tumor marker

22
Q

PC Two biggest risk factors?

A

Tobacco use

ƒChronic pancreatitis (especially > 20 years)

23
Q

Pancreatic cancer presents with?

A

Obstructive jaundice with palpable,
nontender gallbladder

Migratory thrombophlebitis

24
Q

Elderly Female who is thin that has DM?

A

Think pancreatic cancer that knocked out islets

25
Q

Edited**

What is the pathogenesis of acute pancreatitis?

A

Ductal obstruction (via edema/ischemia) OR direct parenchymal injury=>

acinar cell damage=>

intra-acinar conversion of trypsinogen-> trypsin

=>activation of other enzymes=>
i.e. fat necrosis-lipases
autodigestion-proteases
vascular damage-elastase (liquefactive necrosis)