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Principles of Disease > Fungi > Flashcards

Fungi Flashcards

1
Q

What is a Fungi?

A

A spore forming eukaryote that lacks chlorophyll

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2
Q

What substance is commonly found in fungal membranes?

A

Sterol

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3
Q

What is sterol?

A

Steroid alcohol

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4
Q

What is the main sterol found in fungal membranes?

A

Ergosterol

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5
Q

What are the three major groups of fungi?

A

Basidomycetes
Ascomycetes
Zygomycetes

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6
Q

Describe the structure of a Zygomycetes

A

A rough walled zygote containing multiple zygospores

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7
Q

What are yeasts?

A

Fungi that favor a unicellular habit

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8
Q

What is condiium?

A

Nonmotile spores

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9
Q

When would conidiophore be released?

A

When the conditions are less favorable and the fungi begins to form spores

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10
Q

When would infection from a fungi be potentially fatal?

A

When it has infected immunosupperessed patients

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11
Q

What factors increase the pathogenicity of a host?

A

Warm, moist environments

Any immunosupression

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12
Q

What conditions cause immunosuppression?

A

AIDS
HIV
Leukemia

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13
Q

What are the risk factors of candidiasis?

A 
Age
Antibiotic therapy 
Endocrine disorders
Immune suppression
Surgery
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14
Q

What is the most common type of candida species causing infection?

A

Candia albicans

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15
Q

What are the main causative species of aspergillosis?

A

Aspergillus fumigatus

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16
Q

What disease can aspergillosis cause?

A

Asthma

17
Q

What kind of fungi is apergillus?

A

A mould

18
Q

What is the main causative species of cryptococcosis?

A

Cryptococcus neoformans

19
Q

What diseases are caused by Cryptococcus spp?

A

Meningitis

20
Q

What investigations are used to diagnose fungal infections?

A

Direct smear
Detection of fungal antibodies
Culture

21
Q

What are the different classes of anti-fungal drugs?

A

Triazoles
polyenes
flucytosine

22
Q

What do anti-fungal drugs target?

A

Sterols in the fungal membrane

Principles of Disease (10 decks)

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