ADR's

Question 1

Define ADR

Answer 1

Adverse drug reactions are any response to a drug which is unintended even when given at a standard dose for treatment

Question 2

What is the time frame for an acute ADR?

Answer 2

<60 minutes

Question 3

What is the time frame for sub-acute ADR?

Answer 3

1 to 24 hours

Question 4

What is the time frame for latent ARR?

Answer 4

> 2 days

Question 5

What are the three levels of severity of adverse drug reactions?

Answer 5

Mild
Moderate
Severe

Question 6

What are type A ADR’s?

Answer 6

Augmented

Question 7

What are type B ADR’s?

Answer 7

Bizarre

Question 8

What are type C ADR’s?

Answer 8

Chronic

Question 9

What are type D ADR’s?

Answer 9

Delayed

Question 10

What are type E ADR’s?

Answer 10

End of treatment

Question 11

What are type F ADR’s?

Answer 11

Failure of treatment

Question 12

List predisposing factors for ADR’s

Answer 12

Age - young and old
Sex - more common in women
Renal failure
If on multiple drugs

Question 13

What are the features of Type A ADR’s?

Answer 13

Normal but augmented response of drug
Predictable
Dose dependent
Due to excess pharmacological action

Question 14

What factors affect the absorption of a drug?

Answer 14

Dose
GI otility
Formulation
First pass metabolism

Question 15

What are the features of type B ADR’s?

Answer 15

No relation to action of drug
Not dose dependent
Delay between administrating and ADR

Question 16

What are the features of type C ADR’s?

Answer 16

Related to the duration of therapy
Dose not occur on single dose
Semi-predictable

Question 17

What are the features of type D ADR’s?

Answer 17

Occurs a period of time after treatment

Can affect patient of patient offspring

Question 18

What are the features of type E ADR’s?

Answer 18

Occur when drug is stoped suddenly