Fungal Infections of the Respiratory Tract II Flashcards
Where is paracoccidiomycosis often found
tropical regions of south and central america
Is the paracoccidiomycosis more common in men or women
men
Disseminated paracoccidiodomycosis presents as what
chronic cutaneous and mucocutaneous ulcers
What is the distinctive look of paracoccidiomycosis yeast
mickey mouse years
ship’s wheel
Where is coccidiodomycosis often found
US - in CA and AZ
Structure of coccidiodes immitis
after inhalation it converts to aspherule
Symptoms of coccidioidomycosis
mild to moderate flu like symptoms
Disseminate coccidiodomycosis
infection of bones, joints, skin, and CNS
Coccidial menigitis
develops slowly with increasing headache, fever, stiff neck and other neulogical signs. fatal if untreated
How do you treat mild coccidioidomycosis
azole
How do you treat disseminated coccidioidomycosis or menegitis
amphotericineB
What is the leading form of fungal meningitis
cryptoccus neoformans
How can you test for cryptococcus neoformans
india ink stain
Is cryptococcus neoformans dimorphic
NO
it’s always encapsulated yeast
What is cryptococcus neoformans associated with
bird droppings
Cryptococcosis pulmonary disease
asymptomatic mild, spontaneously resolvign flu like illnes
little sputum production
little damage to lung
Cryptococcosis disseminated disease
skin and bone lesions
How do you treat cryptococcosis menigitis
combo of amphotericin B and 5-fluorcytosin or fluconazole
Pneumocystis jiroveci (PCP)
highly lethal form of pneumonia
very common in AIDS patients
charactersitics of PCP
single celled eukaryotic organism
similiar to protozoa
Symptoms of PCP
dyspnea, nonproductive cough, fever, develops weakness, tachypnea, cyanosis and death
How do you treat PCP
trimethoprim-sulfamethoxazole
Is aspergillosis dimorphic
NO always a mold
disseminated aspergillosis infection
invasion of lung parenchyma following infection
fungal hyphae invade lumen and walls of blood vessels, cause thrombosis, infarction and hemorrhage
