Fundamentals of Pathology Flashcards

1
Q

Decrease/Increase in size

A

Atrophy/Hypertrophy

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2
Q

Increase in Number

A

Hyperplasia

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3
Q

One cell type to another

A

Metaplasia

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4
Q

Size, shape, function change such as sickle cell anemia

A

Dysplasia

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5
Q

Disorganization- CANCER

A

Anaplasia

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6
Q

Defective devolopment

A

Hypoplasia

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7
Q

Lack of development

A

Aplasia

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8
Q

Absense of growth

A

Agenesis

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9
Q

Coagulation Infarction

A

MI

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10
Q

Liquefaction degeneration

A

Brain

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11
Q

Caseous degeneration

A

TB, single COIN lesion= Ghon Complex

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12
Q

Enzymatic degeneration

A

Pancreas (Head of pancreas)

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13
Q

Fatty degeneration

A

Liver

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14
Q

Gummatous ***

A

Tertiary Syphilis

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15
Q

Wallerian

A

Peripheral Nerves (Distal–>Proximal)

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16
Q

This includes the lymph capillary network, the lymph nodes and lymph organs. There are mobile and tissue macrophages.

A

Mononuclear Phagocyte System (MPS) aka Reticuloendothelial System (RES)

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17
Q
Immunity cells:
Kupffer cells*-->a
Alveolar macrophages-->b
Microglial cells-->c
Histocytes or fixed macrophages-->d
Dust cells-->e
A

a) Liver
b) Alveoli
c) Brain
d) Tissue
e) Lung

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18
Q

What are the four immunoglobulins?

A

IgA, IgG, IgE, IgM

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19
Q

Immunoglobulin deals with milk, membranes “mommy’s milk”

A

IgA

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20
Q

Immunoglobulin smallest, MOST NUMEROUS

A

IgG

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21
Q

Immunoglobulin deals with AllegIEs and parasites?

A

IgE

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22
Q

Immunoglobulin deals with first response, largest “marine”

A

IgM

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23
Q

What type of immunity involves antibodies B cells. Found in SPLEEN, TONSILS, LYMPH, GI and BONE MARROW

A

Humoral Immunity

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24
Q

What type of immunity deals with Sensitized lymphocyte T CELLS (THYMUS). Protects the body from OWN DEFENSE SYSTEM, BACTERIA, VIRUSES, and PRIONS

A

Cellular Immunity

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25
Q

What are the four hypersensitivities?

A
I AM IT
I-Immediate (Anaphylaxis) bee sting
II- Antibody Mediated (Myasthenia Gravis
III- Immune (SLE, RA)
IV- T CELL mediated, Delayed dermatitis
26
Q

What are the 5 white blood cells (Leukocytes)

A

Neutrophils, Lymphocyte, Monocyte, Eosinophil, Basophil

Never Let My Engine Blow 60, 30, 8 3 0

27
Q

Which WBC is BACTERIAL infection acute infection, phagocytic?

A

Neutrophil

28
Q

Which WBC is VIRAL infection, CHRONIC disease?

A

Lymphocyte

29
Q

Which WBC is for CHRONIC infection?

A

Monocyte

30
Q

Which WBC is PARASITIC and ALLERGIC conditions?

A

Eosinophil

31
Q

Which WBC is similar to MAST CELLS, makes HEPARIN and HISTAMINE?***

A

Basophil

32
Q

Reed Sternberg Cell, relapsing fever, IVORY WHITE VERTEBRA, B CELLS

A

Hodgkin’s Lymphoma

33
Q

Inability to produce antibodies due to lack of B CELLS.

A

Bruton’s Agammaglobulinemia

34
Q

BENCE JONES* proteinuria, MC primary Malignancy of the spine**, M spike, inverted albumin-globulin ratio, Plasma cell tumor.

A

Multiple Myeloma

35
Q

Retrovirus, attacks T4 HELPER CELLS, KAPOSI SARCOMA, parasitic pneumonia.

A

AIDS

36
Q

Autoimmune/MC Hypothyroidism

A

Hashimoto’s

37
Q

Children, aggressive, abdominal mass, “starry Sky”, EBV, can be cured with chemo, Chromosome 8, africa

A

Burkitt’s Lymphoma

38
Q

What are the Ivory White Vertebra?

A

MPH (Metastasis, Paget’s/Osteitis Deformans, Hodgkin’s Lymphoma)

39
Q

Is Metastasis lytic or blastic mostly?

A

Lytic, except for PROSTATE

40
Q

Which one of ivory white vertebrae has lymph cell enlarged concavely?

A

Hodgekins Lymphoma

41
Q

What is present in all leukemias?**

A

ANEMIA

42
Q

Leukemia similar to Burkitt’s lymphoma (starry cell), peaks at 3-4 years old?

A

ALL (Acute Lymphocytic/ Acute Lymphoblastic) Leukemia

43
Q

Leukemia at all ages, peak 40-50 years old, chromosomal abnormality, PHILIDELPHIA chromosome**

A

CML (Chronic Myelocytic aka Chronic Granulocytic) Leukemia

44
Q

Leukemia MC in young adults, peak 15-20 years old,

A

AML (Acute Myeloblastic/ Acute Granulocytic Leukemia)

45
Q

Leukemia MC in ELDERLY

A

CLL (Chronic Lymphocytic Leukemia)

46
Q

Immunodeficiency where Deficiency of PROTEINS ONLY, Pot-belly, Loss muscle mass, rare US Children, 50 % elderly- nursing homes

A

Kwashiorkor Disease** (MC than Marasmus)

47
Q

Immunodeficiency of PROTEINS and CALORIES, World Health Organization says 5 million children die each year from malnutrition* BROOMSTICK ARMS AND LEGS

A

Marasmus Disease*

48
Q

Fluids, proteins, blood cells into interstitial tissue means

A

Exudate

49
Q

Mostly Albumin

A

Transudate

50
Q

Increased Fluid interstitial or serous cavities

A

Edema

51
Q

Purulent exudate (Mostly Neutrophils)

A

Pus

52
Q

Free fluid in peritoneal cavity

A

Ascites

53
Q

Whole body Swollen

A

Anasarca

54
Q

Protein Mediator Activates and Orchestrates inflammation response

A

Cytokines

55
Q

Right side heart failure…

A

Cor pulmonale

56
Q

Berry Aneurysm occurs…

A

Anterior Commissure*

57
Q

Angina at rest…

A

Prinzmetal

58
Q

Dissecting Aneurysm common….

A

Marfan’s

59
Q

Male, Smoker…

A

Buerger’s

60
Q

Apoptosis….

A

Cell Suicide

61
Q

Interleukin- Made by what? **

A

Helper CD4 + T lymhpocytes, monocytes, macrophages, and endothelial cells
“Interleukin Helped Tymphiny’s Mono Making Endothelial Soup”