Blood and Lymphatic Disorders Flashcards
Rare, occurs TERTIARY stage*** syphilis, involves VASA VASORUM, mc in thoracic.
Syphilitic Aortitis
What is the aka for Takayasu’s disease?
Occlusive Thromboaortopathy/ Aortic Arch Syndrome/ Pulseless Disease**
This is rare and involves the AORTIC ARCH
Takayasu’s Disease/ Occlusive Thromboaortopathy/ Aortic Arch Syndrome/ Pulseless Disease
Giant Cell Arteritis is aka?
Temporal Arteritis
Rare, Inflames TEMPORAL and INTRACRANIAL arteries, can cause BLINDNESS. MC vasculitis in ELDERLY.
Giant Cell Arteritis aka Temporal Arteritis **
Rare, young adults, NODULAR REDDISH SWELLING, microaneurysms, narrows arteries from fibrosis, inflm of small arteries. fatal if untreated
Polyarteritis Nodosa
Necrotizing vasculitis, Lungs, nasopharynx, and Kidney (kills vascular area).
Wegener’s Granulomatosis
Primary involvment in the lungs, 5 year survival rate of 25%
Churg & Strauss
Kawasaki aka?
Mucocutaneous Lymph Node Syndrome
This is rare, occurs in CHILDREN, immunologic hypersensitivity, fever, conjunctival and oral edema, hemorrhage, cervical lymphadenopathoy, MI, aneurysms cause death 3% cases. STRAWBERRY TONGUE, MC vasculitis among children.
Kawasaki Disease aka Mucocutaneous Lymph Node Syndrome
Thromboangiitis Obliterans aka?
Buerger’s Disease***
Pain in theLOWER EXTREMITY, SMOKERS, inflm of medium sized arteries, may cause ulcerations and gangrene.
Thromboangiitis Obliterans aka Buerger’s Disease ***
Vasospastic disorder of small arteries (especially hands) Females, Triphasic color change** (White–>Pallor, Blue (Cyanosis), Red (Rubor)
Raynaud’s Disease*
Phlebitis (VEIN Inflammation) Related to a thrombus. Occurs repeatedly in different locations.
Thrombophlebitis/ Thrombophlebitis Migrans/ Migrating Thrombophlebitis
Heme production disrupted, DARK PURPLE URINE
Porphyria
Inheritied, Faulty Synthesis hemoglobin, severy anemia
Thalassemia (alpha and beta) *MICROCYTIC
Lymphadenopathy can be immune response or specific agent. In Immune there are bacterial, cancer, and viral. What are symptoms of each?
Bacterial: Strep throat, syphilis, plague
Cancer: Nodes drain tumor site
Viral: MONO
Lymphadenopathy can be immune response or specific agent. What are some specific agents involved?
Pyogenic Lymphadenitis, infections mononucleosis (EBV), toxoplasmosis, TB, histoplasmosis, Sarcoidosis, RA, Non-Hodgkin’s (no Reed sternburg), Hodgkin’s (Reed Sternberg giant cells)*, Carcinoma, melanoma
Lymphangitis is inflammation of the ____ ____. It occurs as a result of infection at a site ____ to the channel. The MC bacterial organism for bacterial lymphangitis is ____ ____ which causes red streaks.
Lymphatic channels; Distal; Streptococcus pyogenes;
_____ lymphangitis is common in tropics. Organisms for that would include Wuchereria bancrofti and Brugia malayi Aedes and Culex Mosquito bite.
Filarial
Disease where you cannot make glucocerebrosidase. Fat not broken down. Fat accumulates in spleen, liver, bone marrow.
Gaucher’s Disease
Cancer associated with chromosome 8. “Starry Sky”**, Epistein Barr, Chemotherapy. B CELLS
Burkitt’s Lymphoma
