Blood and Lymphatic Disorders

Question 1

Rare, occurs TERTIARY stage*** syphilis, involves VASA VASORUM, mc in thoracic.

Answer 1

Syphilitic Aortitis

Question 2

What is the aka for Takayasu’s disease?

Answer 2

Occlusive Thromboaortopathy/ Aortic Arch Syndrome/ Pulseless Disease**

Question 3

This is rare and involves the AORTIC ARCH

Answer 3

Takayasu’s Disease/ Occlusive Thromboaortopathy/ Aortic Arch Syndrome/ Pulseless Disease

Question 4

Giant Cell Arteritis is aka?

Answer 4

Temporal Arteritis

Question 5

Rare, Inflames TEMPORAL and INTRACRANIAL arteries, can cause BLINDNESS. MC vasculitis in ELDERLY.

Answer 5

Giant Cell Arteritis aka Temporal Arteritis **

Question 6

Rare, young adults, NODULAR REDDISH SWELLING, microaneurysms, narrows arteries from fibrosis, inflm of small arteries. fatal if untreated

Answer 6

Polyarteritis Nodosa

Question 7

Necrotizing vasculitis, Lungs, nasopharynx, and Kidney (kills vascular area).

Answer 7

Wegener’s Granulomatosis

Question 8

Primary involvment in the lungs, 5 year survival rate of 25%

Answer 8

Churg & Strauss

Question 9

Kawasaki aka?

Answer 9

Mucocutaneous Lymph Node Syndrome

Question 10

This is rare, occurs in CHILDREN, immunologic hypersensitivity, fever, conjunctival and oral edema, hemorrhage, cervical lymphadenopathoy, MI, aneurysms cause death 3% cases. STRAWBERRY TONGUE, MC vasculitis among children.

Answer 10

Kawasaki Disease aka Mucocutaneous Lymph Node Syndrome

Question 11

Thromboangiitis Obliterans aka?

Answer 11

Buerger’s Disease***

Question 12

Pain in theLOWER EXTREMITY, SMOKERS, inflm of medium sized arteries, may cause ulcerations and gangrene.

Answer 12

Thromboangiitis Obliterans aka Buerger’s Disease ***

Question 13

Vasospastic disorder of small arteries (especially hands) Females, Triphasic color change** (White–>Pallor, Blue (Cyanosis), Red (Rubor)

Answer 13

Raynaud’s Disease*

Question 14

Phlebitis (VEIN Inflammation) Related to a thrombus. Occurs repeatedly in different locations.

Answer 14

Thrombophlebitis/ Thrombophlebitis Migrans/ Migrating Thrombophlebitis

Question 15

Heme production disrupted, DARK PURPLE URINE

Answer 15

Porphyria

Question 16

Inheritied, Faulty Synthesis hemoglobin, severy anemia

Answer 16

Thalassemia (alpha and beta) *MICROCYTIC

Question 17

Lymphadenopathy can be immune response or specific agent. In Immune there are bacterial, cancer, and viral. What are symptoms of each?

Answer 17

Bacterial: Strep throat, syphilis, plague
Cancer: Nodes drain tumor site
Viral: MONO

Question 18

Lymphadenopathy can be immune response or specific agent. What are some specific agents involved?

Answer 18

Pyogenic Lymphadenitis, infections mononucleosis (EBV), toxoplasmosis, TB, histoplasmosis, Sarcoidosis, RA, Non-Hodgkin’s (no Reed sternburg), Hodgkin’s (Reed Sternberg giant cells)*, Carcinoma, melanoma

Question 19

Lymphangitis is inflammation of the ____ ____. It occurs as a result of infection at a site ____ to the channel. The MC bacterial organism for bacterial lymphangitis is ____ ____ which causes red streaks.

Answer 19

Lymphatic channels; Distal; Streptococcus pyogenes;

Question 20

_____ lymphangitis is common in tropics. Organisms for that would include Wuchereria bancrofti and Brugia malayi Aedes and Culex Mosquito bite.

Answer 20

Filarial

Question 21

Disease where you cannot make glucocerebrosidase. Fat not broken down. Fat accumulates in spleen, liver, bone marrow.

Answer 21

Gaucher’s Disease

Question 22

Cancer associated with chromosome 8. “Starry Sky”**, Epistein Barr, Chemotherapy. B CELLS

Answer 22

Burkitt’s Lymphoma