FUNCTIONS & CLINICALLY SIGNIFICANT ELECTROLYTES Flashcards
What are the FUNCTIONS OF ELECTROLYTES?
*Volume and osmotic regulation
*Myocardial rhythm & contractility
*Neuromuscular Excitability
*Cofactors in enzyme activation
*Regulation of ATPase ion pumps
*Acid-base balance
*Production & use of ATP from glucose
Volume and osmotic regulation
Na, Cl, K
Myocardial rhythm & contractility
Heart activity: K, Mg, Ca
Neuromuscular Excitability
Nerve transfusion, regulates synapse (neuromuscular junction): K, Mg, Ca
Cofactors in enzyme activation
Non-protein substances that enhance enzymatic reactions
Electrolytes that acts as activators: Mg, Ca, Zn
Regulation of ATPase ion pumps
Active transport of ion on cell membrane: Mg
Acid-base balance
Maintains equilibrium in acid-base content of plasma: HCO3-, K, Cl
Production & use of ATP from glucose
During glycolysis: Mg, PO4-
Ex. of Cation Electrolytes
Na+
K+
Ca2+
Mg2+
Cation Extracellular Values
Na+ (136-145)
K+ (3.5-5.1)
Ca2+ (2.15-2.5)
Mg2+ (0.63-1)
Cation Intracellular Values
Na+ (15)
K+ (150)
Ca2+ (1)
Mg2+ (13.5)
Ex. of Anion Electrolytes
HCO3-
Cl-
HPO2-
SO2-
Anion Extracellular Values
HCO3- (23-29)
Cl- (98-107)
HPO2- (0.78-142)
SO2- (0.5)
Anion Intracellular Values
HCO3- (10)
Cl- (1)
HPO2- (50)
SO2- (10)