Functional histology of the lungs Flashcards

1
Q

what are the three principle compartments of the respiratory system

A
  • Conduction zone
  • Respiratory zone
  • Musco-elastic ventilation apparatus
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2
Q

What does the conduction zone do

A

Conditions inhaled air

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3
Q

What does the respiratory zone do

A

Site of gas exchange

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4
Q

What does the music-elastic ventilation apparatus do

A

Drives ventilation

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5
Q

What does air come in through and what happens here

A

Nasal cavity

-air gets swirled around

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6
Q

Where does air go after the nasal cavity

A

Nasopharynx and then the trachea through the voice box

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7
Q

What is the gas exchange region in the lungs called

A

Distal respiratory tree

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8
Q

What are airways kept open by and why

A

Bony/cartilaginous scaffolds

-To cope with changing pressure

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9
Q

What do turbinate bone do an where are they

A

In the nasal cavity and they form narrow passageways that create turbulence so drive air in and out of the sinuses because opening of sinuses is very small

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10
Q

How is temperature adjustment and moisturizing enhanced

A

Due to large venous plexus in the submucosa

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11
Q

How are large particles prevented entry

A

By vibrissae (small hairs at entry to nasal cavity)

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12
Q

What is the epithelium of the respiratory tract to the bronchioles

A

Respiratory epithelium

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13
Q

What is below the epithelium

A

Mucosa has a sponge like epithelium due to the extensive venous plexus

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14
Q

What does the venous plexus do

A

Mediate exchange of moisture with the air; their filling status also relates the flow of air through the nasal cavities

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15
Q

What is on top of the nasal cavity

A

Olfactory elithelium

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16
Q

What does the olfactory epithelium do

A

Conveys the sense of smell

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17
Q

What do the cilia on the olfactory epithelium carry

A

Odorant receptors

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18
Q

what do the central processes of the olfactory processes of the olfactory receptor neurons in the olfactory epithelium unite to form

A

Nerve bundles that pass through the crifriborm plate (which collectively constitute the olfactory nerve) and enter the olfactory bulb

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19
Q

What is the trachea kept open by

A

Horse shoes shaped cartilage

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20
Q

What glands does the trachea have and where

A

Seromucous glands in the submucosa

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21
Q

What completes the rings which are partially formed by the cartilage

A

Smooth muscle

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22
Q

What does respiratory epithelium consist of

A

Pseudostratified, ciliated epithelium of varying thickness (depending on region) with mucous producing goblet cells

23
Q

What areas ave additional seromucuous glands in their submucosa

24
Q

What is mucociliary clearance

A

Mucus getting transported towards the pharynx by constantly beating cilia

25
What does bronchus haven its wall
cartilage
26
what is the lumen of bronchus bordered by
Respiratory epithelium
27
When there is an incomplete ring of smooth muscle located between the epithelium and cartilage, what may be present
Submucosal glands
28
what does the presence of cartilage mean
It is a bronchus
29
How are the bronchioles different from bronchi
- No cartilage in its wall - Epithelium is smaller and the cells are not columnar anymore - Fewer goblet cells
30
What is the epithelium of the smaller bronchioli like
Cells become cuboidal and the cells consist of ciliated and non-ciliated club cells
31
What is the role of club cels
Protective role as they generate serous secretions
32
What surround the epithelium in smaller bronchioli
complete ring of smooth muscle
33
What is the ration of muscle ring thickness to luminar diameter like in bronchioli than bronchi
Higher
34
What does the bronchiolar constriction induce
High airway resistance
35
What do terminal bronchioles give rise to
Respiratory bronchioles that have cuboidal epithelium and alveoli built in their walls
36
What does the connective tissue of the alveoli and the lower airways contain
Numerous elastin fibres
37
What is the blood air barrier in the alveoli built of
Ultra thin walls of capillary endothelium and type 1 cells
38
Where is the blood supply to the alveolar capillary networks from
Pulmonary circulation (which are elastic to distal part)
39
What are pulmonary arteries like
Elastic arteries with comparatively thin walls
40
What are do the larger pulmonary arteries accompany
bronchi and bronchioli
41
What do the bronchi have their own blood supply from
aorta which are muscular
42
What are the bronchial arteries like
Small strong muscular wall like elastin
43
Why are surfactants used
Because in a space of such a small diameter as an alveolus, any water on the alveolar surface would exert strong capillary forces which would inhibit the expansion of the lung
44
What do surfactants do
Reduce surface tension
45
Where are the lymph vessels of the lung's lymphatic drainage system found
In the septa next to the vessels of the pulmonary circulation
46
What do the lymph vessels in the lung drain into
A series of major lymph nodes along the trachea
47
Where are there also a network of lymph vessels
Interstitial layer adjacent to the pleura
48
Where are tonsils found
In oral and nasal cavity
49
What are tonsils
Antigen presentation sites which have access to the airways
50
How many tonsils are there in nasal cavity
5
51
What is Waldeyer's ring
Ring of tonsils at the anterior pharynx which are basically aggregates of lymph follicles
52
What do the mucus of the airways contain
immunoglobins
53
What are the primary line of defense in alveoli
alveolar macrophages