Biological role of respiration, histology and defence mechanisms Flashcards

1
Q

What are the three principle compartments of the respiratory system

A

Conduction Zone: Conditioning of inhaled air

Respiratory Zone: Site of gas exchange

Musculo-elastic ventilation appararatus: Drives ventilation

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2
Q

What are airways kept open by

A

Either bony or cartilaginous scaffolds

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3
Q

What is the role of turbinate bones in the nasal cavity

A

Form narrow passageways that create turubulence, driving air in and out of sinuses which enhances surface to air volume ratio

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4
Q

What adjusts the temperature and moisturises air

A

Large venous plexus in the submucosa

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5
Q

Where does mucus lie in the nasal cavity

A

Lining all the way to the terminal bronchioles

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6
Q

What is the epithelium of the respiratory tract

A

respiratory type

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7
Q

What do the veins of venous plexus in mucosa do

A

Mediate exchange of moisture with the air; their filling status also regulates the flow of air through the nasal cavity

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8
Q

What is the role of the olfactory epithelium

A

Conveys the sense of smell

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9
Q

What does the respiratory epithelium consist of

A

-Pseudostratified, ciliated epithelium of varying thickness with mucous producing goblet cells

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10
Q

What is the bronchial lumen bordered with

A

Respiratory epithelium

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11
Q

What does the bronchus contain

A

Incomplete ring of smooth muscle located between the epithelium and cartilage

Cartilage on its wall

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12
Q

What does a bronchioles not have

A

Cartilage on its wall

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13
Q

How does a bronchiole differ from a bronchus

A
  • Fewer goblet cells
  • Complete ring og sooth muscle surrounding the epithelium
  • No submucosal glands
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14
Q

What does the epithelium of the smaller bronchiole become

A

Cuboidal

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15
Q

What does the epithelium of the smaller bronchioli consist of

A

Ciliated cells as well as non-ciliated club cells

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16
Q

What is the role of club cells

A

Have a protective role - generate serous secretions

17
Q

How does bronchioli differ to bronchi

A

Ratio of muscle ring thickness to luminal diameter is higher as bronchiolar constriction induces high airway resistance

18
Q

What does the connective tissue of the alveoli and the lower airways contain

A

Numerous elastin fibres

19
Q

Where is the blood supply to the alveolar capillary network from

A

Pulmonary circulation

20
Q

Where do the bronchi have their own blood supply from

A

Aorta (bronchial circulation)

21
Q

What is the role of a surfactant

A

reduce surface tension which allows the expansion of the lung and prevents the collapse of the alveoli

22
Q

What produces surfactant

A

type 2 pneumocytes

23
Q

What are the pleural walls covered with

A

Simple squamous epithelium

24
Q

What do the elastic fibres in the interstitial spaces in the alveoli do if the pleural cavity is pierced

A

Cause a lung to shrink

25
Q

Where are the lymph vessels of the lung’s drainage system found

-Where do they drain

A

In septa next to the vessels of the pulmonary circulation

-Drain into major lymph nodes along the trachea