Formative Questions Flashcards
Which of the following is used in HIV therapy?
Saquinavir
Which of the following is used in the treatment of UTIs?
Nitrofurantoin
Serious infections with MRSA require treatment with what?
IV Vancomycin
Serious infection with a gram negative organism such as E-coli should be treated with what?
IV gentamicin
Serious systemic fungal infections require treatment with intravenous what?
Amphotericin B
The pathogenesis of systemic type III hypersensitivity requires what?
Immune complex formation
Neurophil polymorphs are a major component of what?
Acute inflammatory response
Fibroblasts produce what?
Collagens
What does histamine do in acute inflammation?
Relax vascular smooth muscle
What do hypoxia impede?
Tissue healing
GTN is administered by sublingual route to avoid what?
First Pass Metabolism
A drug trial in which neither patient nor doctor is aware what treatment the patient is taking is called a what?
Double blind trial
A drug trial in which data is collected from case records after treatment is given is called what?
Retrospective trial
A drug trial in which patients take both treatments being tested one after the other is called what?
Cross-over trial
A drug trial in which patients are allotted to treatment groups using random number generation is called what?
Randomised trial
The adapter molecule that acts between the coded amino acid and the mRNA in the process of transcription and translation?
tRNA
Only one side of DNA is replicated during what process?
Transcription
A process that requires cooperation and coordination between mRNA, rRNA and tRNA is what?
Protein synthesis
mRNA is used to form an amino acid sequence during the process of?
Translation
The primary site of protein synthesis is where?
The ribosome
The X chromosome can be transmitted by fathers to who?
Daughter but not sons
The Y chromosome can only be transmitted by who?
Fathers
Retinoblastoma is caused by what?
Loss of a tumour suppressor gene
Leukaemia is a malignant tumour of what?
A white blood cell
What kind of tumour is liposarcoma?
Malignant tumour of fatty tissue
What is the name given to a malignant tumour of the glandular epithelium?
Adenocarcinoma
