Formative Questions Flashcards

1
Q

Which of the following is used in HIV therapy?

A

Saquinavir

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2
Q

Which of the following is used in the treatment of UTIs?

A

Nitrofurantoin

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3
Q

Serious infections with MRSA require treatment with what?

A

IV Vancomycin

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4
Q

Serious infection with a gram negative organism such as E-coli should be treated with what?

A

IV gentamicin

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5
Q

Serious systemic fungal infections require treatment with intravenous what?

A

Amphotericin B

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6
Q

The pathogenesis of systemic type III hypersensitivity requires what?

A

Immune complex formation

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7
Q

Neurophil polymorphs are a major component of what?

A

Acute inflammatory response

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8
Q

Fibroblasts produce what?

A

Collagens

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9
Q

What does histamine do in acute inflammation?

A

Relax vascular smooth muscle

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10
Q

What do hypoxia impede?

A

Tissue healing

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11
Q

GTN is administered by sublingual route to avoid what?

A

First Pass Metabolism

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12
Q

A drug trial in which neither patient nor doctor is aware what treatment the patient is taking is called a what?

A

Double blind trial

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13
Q

A drug trial in which data is collected from case records after treatment is given is called what?

A

Retrospective trial

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14
Q

A drug trial in which patients take both treatments being tested one after the other is called what?

A

Cross-over trial

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15
Q

A drug trial in which patients are allotted to treatment groups using random number generation is called what?

A

Randomised trial

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16
Q

The adapter molecule that acts between the coded amino acid and the mRNA in the process of transcription and translation?

A

tRNA

17
Q

Only one side of DNA is replicated during what process?

A

Transcription

18
Q

A process that requires cooperation and coordination between mRNA, rRNA and tRNA is what?

A

Protein synthesis

19
Q

mRNA is used to form an amino acid sequence during the process of?

A

Translation

20
Q

The primary site of protein synthesis is where?

A

The ribosome

21
Q

The X chromosome can be transmitted by fathers to who?

A

Daughter but not sons

22
Q

The Y chromosome can only be transmitted by who?

A

Fathers

23
Q

Retinoblastoma is caused by what?

A

Loss of a tumour suppressor gene

24
Q

Leukaemia is a malignant tumour of what?

A

A white blood cell

25
Q

What kind of tumour is liposarcoma?

A

Malignant tumour of fatty tissue

26
Q

What is the name given to a malignant tumour of the glandular epithelium?

A

Adenocarcinoma