Formation Of Thrombin From Prothrombin

Question 1

1

Factor Xa (prothrombin
activator) converts prothrombin to ________, in the presence of platelet phospolipid, calcium and activated factor _____ (___).

Answer 1

thrombin
V, Va;

Question 2

2

Factor Va (_______) acts as cofactor for acceleration of this process.

Answer 2

proaccelerin

Question 3

Thrombin formation occurs rapidly:

Factor _____ is prothrombin, a vitamin ____ dependent plasma protein continually formed in ______.

Answer 3

II; K
Liver

Question 4

Prothrombin forms thrombin, which is basically a _______ enzyme.
It is formed “rapidlyand in large amount as both intrinsic and extrinsic mechanisms stimulate its formation

Answer 4

proteolytic

Question 5

Once a critical amount of thrombin is formed, a ______ feedback develops – more _______ and more thrombin formed – blood clot grow until blood leakage ceases

Answer 5

positive; clotting