Forces acting on membranes Flashcards
What kind of membrane proteins can’t be removed without disrupting the membrane?
Integral Membrane Proteins (Ampipathic, same orientation as phospholipids)
What kind of membrane proteins can be removed without disrupting the membrane?
Peripheral Membrane Proteins. (Not ampipathic, cell shape and motility)
Dystrophin is an example of what kind of membrane protein and what disease results from a deficiency of it?
Peripheral. Muscular Dystrophy.
What factors is diffusion aided by?
A large surface area
High permeability
High conc. gradient
What do molecules need to be to pass through the lipid bilayer?
Small
Uncharged
Lipophilic (Hydrophobic)
What are the two general types of protein channels
Voltage Gated
Ligand Gated
Does the Inside or the outside of the cell carry a negative charge?
The Inside
What are the two types of carrier mediated transport systems?
Facilitated Diffusion- needs no direct energy source
Active Transport-requires ATP (Na/K pump)
What is Osmolarity?
The number of osmoles of solute per litre of solution.
What is Osmolality?
The measure of osmoles of solute per kilogram of solvent.
If a cell is placed in a Hypertonic solution, what will happen to it?
shrink
If a cell is placed in a Hypotonic solution, what will happen to it?
It will Swell and burst
What is tonicity determined by
the concentration of non-penetrating solutes on either side of the cell
What is an isosmotic solution
There is an equal number of both penetrating and non penetrating solutes on either side of the cell membrane
What is an isotonic solution
There is an equal number of non-penetrating solutes on either side of the cell membrane