Foodborne Dz And Outbreak Investigation Flashcards

1
Q

Origins of food borne hazards

A

> e.coli
- present in water, cattle act as reservoir (manure infects)
campylobacter
- in environment introduced in broilers houses
listeria
- envirment contamination (steel pipes drains etc.)

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2
Q

Give egs. Foodborne illness caused by biological, chemical and physical hazards

A

> Biological
- animal, human or envirment origins
Chemical and physical eg. Dioxins and mycotoxins transmissable by food of animal origin

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3
Q

Which food borne dz has highest mortality rates?

A

Listeria (proportionally)

> but the public health impact is a function of the fatality rate and the incidence of infection

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4
Q

Which is the highest number of cases impact pathogens of foodborne dz (UK)

A
  • campylobacter over half

- norovirus

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5
Q

Outline FSA priority list of foodborne diseae from the 2010-2015 action plan

A
> campylobacter 
> listeria
> e. Coli
> salmonella 
> norovirus 
> clostridium  perfringens
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6
Q

Which food group has the highest risk of food borne disease per serving

A

Poultry (compared to cooked vegetables)

  • eggs
  • red meat
  • sea food
  • milk
  • other dairy lowest risk
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7
Q

Sources of campylobacter

A
  • endemic in animals (poultry, cattle, sheep, pigs)

- sources food and nonfood eg. Untreated water

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8
Q

Clinical signs campylobacter

A
  • incubation period 2-5d
  • d+ and abdo pain
  • self limiting in 10d
  • rare sequalae : Guillan Barre syndrome
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9
Q

How does seasonal incidence of campylobacter change ?

A
  • seasonal peak late spring and summer (maybe d/t flies? Not known)
  • mirrored by humans (sometimes this proceeds the poultry rise!!)
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10
Q

Aim of FSA 2010-2015 wrt campy?

A

Decrease numbers of highly contaminated chickens from 27% to 10%
> hasn’t happened!!!

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11
Q

How can campylobacter tried be managed?

A
  • NB even doing these things risk of campy infection is VERY HIGH*
    > on farm
  • biosecurity fly screen, feed and water additive, vax, genetic resistance
    > farm level management or husbandry
  • thinning or partial depopulation strong risk factor for flock colonisation
    > slaughter and processing
  • campy+ flocks cross contaminate at abbattoir , slaughter last
    > freezing/hot water/chemical decontamination
    > consumer
  • cook properly, avoid cross contamination
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12
Q

Second most common cause of food borne dz in UK?

A

Salmonella

  • and most common pathogen causing food borne OUTBREAKS across the WHOLE EU
  • cf. campy which causes sproadic cases NOT outbreaks
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13
Q

Trend of salmonella case

A

Decreasing but still high (s. Enteridis poultry)

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14
Q

Clinical signs salmonella

A
  • incubation period 12-48hrs
  • VD+ abdo pain and fever
  • self limiting 3-5d
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15
Q

Which sero are of salmonella exist?

A
  • s. Dublin cattle
  • s. Diarizonae sheep
  • s. Typhimurium pigs
    > s. Enteridis POULTRY most successful cause of decrease in salmonella cases
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16
Q

Where is salmonella a hazard?

A
  • raw egg (mayonnaise, ice cream)
  • eggs contaminated before shell is formed
  • pasteurisation destroys
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17
Q

Hazards milk and milk produce

A
  • TB
  • Brucella
  • Salmonella
  • Campylobacter
  • Listeria monocytogenes
  • Staph aureus
  • Bacillus spp.
18
Q

Which hazards in raw milk are destroyed by heat treatment

A
  • TB
  • brucellosis
  • salmonella
  • campylobacter
19
Q

Give 3 pathogens that may pose a risk despite heat tx of milk

A
  • listeria monocytogenes
  • staphylococcal aureus
  • bacillus spp.
20
Q

Sources listeria monocytogenes

A
  • infected animals
  • environment
  • silage
  • BIOFILMS in food processing environment
21
Q

Infective dose of listeria and risk foods

A

> low

  • raw milk
  • chilled ready to eat foods (long shelf life when chilled, no need to cook before eating)
  • sandwiches
  • pate
  • soft mould rippened cheese
  • cooked sliced meats
  • smoked salmon
22
Q

Does heat Tx destroy listeria?

A

Not all but enough to render it safe

- post-pasteurisation contamination main risk

23
Q

Listeria Clinical signs and Risk management listeria monocytogenes

A

> CS
- incubation period LONG ~1month
-non-invasive: flu like symptoms/asymptomatic
- invasive: abortion, meningioencephalitits in children elderly and immunocompromised
risk management
- only causes illness in limited subset of population (target at risk groups)
- industry compliance and enforcement (listeria widespread in environment but need to minimise growth to harmful levels)
- consume food in date

24
Q

Why is bacillus cereus a risk

A
  • produces spores that survive pasteurisation
  • it grows at 5* and produces a toxin
    > need proper refrigeration
  • usually spoils milk before toxin produced so not often consumed
25
Why does staph aureus cause problems?
- post pasteurisation contamination from asymptomatic carrier worker people - staphylococcal enterotoxins formed in food are consumed
26
Hazards in pork
- salmonella - yersinia enterocolitica - hepatitis e - campy - trichinella - aeromonas (spoilage pathogen)
27
Yersinia in pigs
- very common in pigs asymptomatic - undercooked pork - other vehicles untreated water and unpasteurised milk > in humans usually resolves on its own but more severe young and elederly
28
How has hepatitis E incidence changed? Likely source?
- massively increased numbers native humans over last few years - Pigs very often carriers - ^ risk of hepatitis E with processed pork consumption - makes over 45 years old over represented
29
Hazards in beef
``` > e.coli 0157 - feacal contamination mince meat > aeromonas (spoilage) > prions (BSE) > clostridium perfringens ```
30
E. Coli 0157 clinical signs and infective dose needed
- low dose needed - VD+ abdo pain - haemorrhage colitis - most severe children and the elderly - haemolytic uraemia syndrome(HUS) - renal failure and death
31
Vehicles for E.coli infection and therefore risk management strategies
- undercooked mince meat - direct contact open farms - prevalence in cattle up to 20% > prevention - farm biosecurity - slaughter hygiene
32
Hazards in fish and shellfish
> hepatitis A > norovirus - raw seafood eg. esp oysters (virus not destroyed as not cooked) > vibrio spp. - raw seafood eg. esp oysters (virus not destroyed as not cooked) > environmental contaminants
33
why do shellfish pose a health risk?
- filter large volumes of water, accumulate pathogenic viruses and bacteria
34
Risk management shell fish
- relaying (moved to clean area of water for min 2 months before harvest) - depuration (placed in tanks of clean re-circulating sea water tx with UV radiation min 42hrs) > this is v effective for bacteria, less so for viruses
35
Hazards in honey
- clostridium botulinum - environmental contaminants - antimicrobial residues
36
Why should children not consume honey?
Potential for clostridial botulinum spores to grow in intestinal tract of very young children
37
Are all foodborne dz zoonotic?
- not all foodborne illness is zoonotic | - not all zoonoses are foodborne
38
Infectious dose, pathophysiology of botulism
> extremely potent low dose needed - c. botulinum ubiquitous in soil, sediments, water etc. - growth of pathogen ANAEROBIC conditions only - home canned or fermented stuff
39
Clinical signs botulism in humans. Tx?
- incubation time 12-36hrs - tx: antitoxin - can be fatal > infant botulism if bacteria colonises large intestine
40
Give 2 "processing" hazards
> staph aureus - on food handlers - produces toxin - high risk products: custard, whipped cream > clostridium perfringen s - present in environment and raw meat - inadequate temperature control during cooking -> spores can germinate and bacteria can grow - high risk products: stew, long, slow cooking
41
egs. chemical hazards in food
- heavy metals - halogenated hydrocarbons - insecticides - fertilisers - hormone like GP/antimicrobial GP - biogenic amines - MYCOTOXINS - meat conservation - packaging > see table for more egs./
42
Which hazards can accumulate in the food chain? How are these monitored/controlled?
- heavy metals, halogenated hydrocarbons, insecticides (DDT) - toxicity mostly chronic (carcinogens, teratogens) > max levels (WHO/FAO) monitored by UK FSA and DEFRA > recall of products if higher than max allowed (eg. Dioxins in pork) > VMD statutory residue surveillance for vet medicines and environmental residues