folate deficiency

Question 1

where is folic acid found?

Answer 1

folate is found in green vegetables

Question 2

how is folate absorbed?

Answer 2

1. found in green vegetables
2. absorbed in duodenum and jejunum
3. folate is stored in liver

Question 3

clinical features

Answer 3

1. fatigue
2. pallor
3. glossitis
4. v similar to b12 symptoms

Question 4

clinical features - folate deficiency vs b12

Answer 4

FOLATE DEFICIENCY DOES NOT RESULT IN NEUROLOGICAL SYMPTOMS

Question 5

Name 3 major causes of folate deficiency?

Answer 5

1. decreased intake - poor diet
2. decreased absorbtion
   - coeliac’s
   - inflammatory bowel disease
3. Increases RBC requirement
   - haemolytic anaemia
   - pregnancy
4. ALCOHOL USE

Question 6

Name 3 drugs which causes folate deficiency?

Answer 6

1. Alcohol
2. anti epileptic drugs - Phenytoin
3. Trimethoprim / methotrexate

Question 7

Treatment of folate deficiency

Answer 7

oral folate supplements for 4 months minimum