anaemia of chronic disease Flashcards

1
Q

what is anaemia of chronic disease?

A

anaemia as a result of chronic inflammatory conditions

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2
Q

What is hepcidin?

A

Hepcidin - major iron regulator

  1. iron reduced - increased hepcidin levels
  2. iron increased - reduced hepcidin levels
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3
Q

what happens to Hepicidin levels in iron deficiency anaemia?

A
  1. hepcidin is released in response to chronic inflammation

2. reduce serum iron as iron needed for bacteria to grow

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4
Q

Iron studies results

A
  1. reduced iron
  2. reduced transferrin
  3. reduced total iron binding capacity
  4. increased Ferritin
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