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Physiology > Focus 6 > Flashcards

Focus 6 Flashcards

1
Q

Muscle cell membrane

A

Sarcolemma

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2
Q

Thick filament of the sarcomere

A

Myosin

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3
Q

Thin filament of the sarcomere

A

Actin

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4
Q

What are the levels of organization of skeletal mm (simple-complex)

A
  • myofilament
  • sarcomere
  • myofibril
  • mm fiber
  • fascicle
  • muscle
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5
Q

Thick filament

A

Myosin

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6
Q

Series of events linking excitation to mm contraction. (Cross-bridge activity)

A

Excitation Contraction Coupling

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7
Q

Functional unit of mm cells

A

Sarcomere

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8
Q

Regulatory proteins (accessory proteins)

A

Troponin/tropomyosin

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9
Q

Similar to EPSP but much greater. Potential change=

A

EPP (End Plate Potential)

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10
Q

Part of mm cell containing Ca++

A

Sarcoplasmic reticulum

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11
Q

Carries the AP deep into the mm cell itself

A

T-tubules

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12
Q

Changes shape, sliding tropomyosin out of the way freeing up binding sites

A

Troponin

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13
Q

Thin filament

A

Actin

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14
Q

Ca++ binds with _________ causing ________ to change shape allowing myosin to bind with actin

A

Troponin

Tropomyosin

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15
Q

ATP is required to:

-

A
  • form cross bridge
  • break cross bridge
  • pump Ca++ (active transport pump) back into sarcoplasmic reticulum
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16
Q

ATP is generated by:

-

A
  • creative phosphate
  • anaerobic glycolysis
  • aerobic respiration
17
Q

Glycogen broken down into glucose. Lactic acid released

A

Anaerobic glycolysis

18
Q

This happens so we don’t run out of ATP

A

Muscle fatigue

19
Q

Oxygen required to replace depleted muscle energy stores (return to homeostatic levels)

A

Oxygen debt

20
Q

A lot of ACh + a lot of receptors =

A

No summation required

21
Q

Myosin heads have two sites

A

Actin-binding site

Myosin ATPase site

22
Q

Made up of sarcomere -> thick/thin filament

A

Myofibril

23
Q

Forms the neuromuscular junction. Fits into depression in mm fiber

A

Terminal buttons

24
Q

Each mm fiber contracts all the way

A

All or nothing law

25
Q

Allows mm contraction with varying force. Innervation of more or less cells of a mm

A

Recruitment

26
Q

Allows fine control movement

A

Small motor unit

27
Q

Allows for powerful contractions

A

Large motor unit

Physiology (13 decks)

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