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FMS > FMS Week 9: Regeneration and Repair > Flashcards

FMS Week 9: Regeneration and Repair Flashcards

1
Q

Causes of Tissue Injury

8 Listed

A
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2
Q

Tissue Adaptations

4 Listed

A
  • Hyperplasia
  • Hypertrophy
  • Atrophy
  • Metaplasia
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3
Q
A
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4
Q

What do you see?

A
  • Stratum corneum destroyed
  • neutrophils (forbidden this is acute process)
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5
Q

What do you see?

A

neutrophils in the epithelium (forbidden than is an acute process)

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6
Q

Integrins action

A

signal transduction that there is damage taking place

what is the signal saying?

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7
Q

What is this and its significance in injury?

A

The basement membrane divides to replace dying cells from damage detected by integrin signaling

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8
Q

Macrophage Growth Factors

4 Listed

A
  • EGF
  • TGF-α
  • FGFs
  • TGF-β
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9
Q

What are these cells?

A
  • showing keratinocytes
  • macrophage bot left
  • top right fibroblast
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10
Q

What is the chance there will be regeneration here?

6 Listed

A
  • None
  • very necrotic
  • no cells left
  • angiogenesis will take place
  • macrophages and mesenchymal will come in VEGF, FGF
  • fibroblasts lay down collagen and scar formation
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11
Q

What do you see?

A

granulation tissue

blood vessels

fibroblasts

construction site

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12
Q

What do you see?

A
  • granulation tissue
  • blood vessels
  • fibroblasts
  • construction site
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13
Q
A

scar

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14
Q
A
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15
Q

How is collagen made?

A

need vitamin C for tissue repair

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16
Q

Tissue Examples based on proliferative capacity

3 Listed

A
  • Permanent Tissues
  • Stable Tissues
  • Labile Tissues
17
Q

Permanent tissues Properties

3 Listed

18
Q

Permanent Tissue Examples

2 Listed

A
  • Neurons
  • Cardiac Muscle Cells
19
Q

Stable Tissues Properties

6 Listed

20
Q

A Stable tissue that can divide?

A

Liver Cells

21
Q

Stable Tissues Cell Cycle

A

Tend to be quiescent in G0 but can go back into the cell cycle

22
Q

Labile Tissues Properties

4 Listed

23
Q

Labile Tissue Examples

3 Listed

A
  • Hematopoietic cells of bone
  • Surface epithelia
  • Gastrointestinal columnar epithelium
24
Q

Stem Cell Homeostasis

25
Q

Stem Cell Self-renewal

A

permits stem cells to maintain their numbers

26
Q

Stem cell asymmetric division

A

one daughter cell enters a differentiation pathway and gives rise to mature cells, while the other remains an undifferentiated and retains its self renewal capacity

27
Q

Quality or adequacy of tissue repair may be negatively affected by?

6 Listed

28
Q

First Intention Properties

3 Listed

29
Q

Second intention Properties

6 Listed

FMS (34 decks)

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