FMS Week 9: Pathology of Autoimmunity

Question 1

Autoantibodies with

3 Listed

Answer 1

• Presence of an immune reaction against specific self-antigen or self-tissue
• Evidence that the immune reaction is the primary process
• An absence of another well-defined cause of the disease

Question 2

Autoimmune Diseases mediated by AutoAntibodies

7 Listed

Answer 2

* are systemic

Question 3

Autoimmune Diseases Mediated by T cells

5 Listed

Answer 3

* are systemic

Question 4

Autoimmune Diseases Postulated to be Autoimmune

5 Listed

Answer 4

* are systemic

Question 5

Clinical manifestations of Autoimmune diseases depend on…

Answer 5

Question 6

Autoimmune disease are Acute/Chronic with?

Answer 6

Question 7

Autoimmune Atrophic Gastritis: Parietal Cells function

2 listed

Answer 7

Question 8

Intrinisic factor is important for?

Answer 8

Vitamin B₁₂ transport

Question 9

Parietal Cells secrete

Answer 9

• Hydrochloric acid
• Intrinsic factor

Question 10

Autoimune Atrophic Gastritis

Answer 10

Achlorhydria Decrease in HCL from the destruction of parietal cells which secrete HCL

Question 11

Absorption of B12

4 Listed

Answer 11

Question 12

Without parietal cells what happens with gastrin?

Answer 12

No parietal cells results in high gastrin which is a growth factor and can have neoplasia

Question 13

Autoimmune Atrophic Gastritis

Answer 13

Decreased parietal cells

Question 14

Autoimmune Thrombocytopenia

Answer 14

Prevent blood loss

this is a platelet

Question 15

Answer 15

Increased destruction

Question 16

Normal Knee Joint

3 Listed

Answer 16

Question 17

Rheumatoid Arthritis Description

3 Listed

Answer 17

Question 18

Rheumatoid Arthritis Symmetry

Answer 18

Question 19

Answer 19

Bilateral joint pain and swelling in her wrists

Question 20

Rheumatoid vs Osteoarthritis

Answer 20

Question 21

Good Pasture Syndrome AKA

Answer 21

Anti-GBM Disease

Question 22

Goodpasture Syndrome Description

3 Listed

Answer 22

Question 23

Answer 23

Alveolar Hemorrhage

Question 24

Good pasture syndrome most commonly affects the?

Answer 24

Lungs and the kidneys

Question 25

Graves Disease Description

Answer 25

antibody stimulation of thyroid

Question 26

Thyroid Gland description 4 Listed

Answer 26

Question 27

Answer 27

Weight loss despite normal eating habits