FMS Week 9: Pathology of Autoimmunity Flashcards
Autoantibodies with
3 Listed
- Presence of an immune reaction against specific self-antigen or self-tissue
- Evidence that the immune reaction is the primary process
- An absence of another well-defined cause of the disease
Autoimmune Diseases mediated by AutoAntibodies
7 Listed
* are systemic
Autoimmune Diseases Mediated by T cells
5 Listed
* are systemic
Autoimmune Diseases Postulated to be Autoimmune
5 Listed
* are systemic
Clinical manifestations of Autoimmune diseases depend on…
Autoimmune disease are Acute/Chronic with?
Autoimmune Atrophic Gastritis: Parietal Cells function
2 listed
Intrinisic factor is important for?
Vitamin B12 transport
Parietal Cells secrete
- Hydrochloric acid
- Intrinsic factor
Autoimune Atrophic Gastritis
Achlorhydria Decrease in HCL from the destruction of parietal cells which secrete HCL
Absorption of B12
4 Listed
Without parietal cells what happens with gastrin?
No parietal cells results in high gastrin which is a growth factor and can have neoplasia
Autoimmune Atrophic Gastritis
Decreased parietal cells
Autoimmune Thrombocytopenia
Prevent blood loss
this is a platelet
Increased destruction
Normal Knee Joint
3 Listed
Rheumatoid Arthritis Description
3 Listed
Rheumatoid Arthritis Symmetry
Bilateral joint pain and swelling in her wrists
Rheumatoid vs Osteoarthritis
Good Pasture Syndrome AKA
Anti-GBM Disease
Goodpasture Syndrome Description
3 Listed
Alveolar Hemorrhage
Good pasture syndrome most commonly affects the?
Lungs and the kidneys
Graves Disease Description
antibody stimulation of thyroid
Thyroid Gland description
4 Listed
Weight loss despite normal eating habits
