Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FMS > FMS Week 9: Pathology of Chronic Inflammation > Flashcards

FMS Week 9: Pathology of Chronic Inflammation Flashcards

1
Q

Features of Acute Inflammation

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Features of Chronic Inflammation

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

chronic inflammation is an outcome of?

A

Acute inflammation if the cause is not resolved

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Causes of Chronic Inflammation

7 Listed

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
A

Tuberculosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tissue/Pathology?

A

Normal Lung Alveoli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tissue/Pathology?

A

Tuberculosis associated with necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tissue/Pathology?

A

Tuberculosis associated with necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Immune granulomas are caused when?

A

The inciting agents are difficult to eradicate, such as a persistant microbe or self-antigen

Persistant Infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cells in Chronic Inflammation

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Tissue/Pathology?

A

Normal Lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Tissue/Pathology?

A

Sarcoidosis

NOT associated with necrosis

A lot of fibrosis and fibroblasts

no neutrophils so chronic

Langerhans giant cells seen top right

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Tissue/Pathology?

A

Sarcoidosis

NOT associated with necrosis

A lot of fibrosis and fibroblasts

no neutrophils so chronic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Hypersensitivity Disease Properties

4 Listed

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Macrophage effector functions for inflammation and Tissue Injury

7 Listed

A
18
Q

Macrophage effector functions for Repair

4 Listed

A
19
Q
A
20
Q
A
21
Q

Tissue/Pathology?

A

Normal Colon

22
Q

Tissue/Pathology?

A

Crohn’s Disease

Architectural changes (Acute and Chronic)

lamina propria packed full of inflammatory cells

branching of glands, only one normal looking gland

has neutrophils because there is an acute aspect of IBD

23
Q

Tissue/Pathology?

A

IBD associated cancer

Colorectal Adenocarcinoma

arising from chronic inflammation from Crohn’s Disease

24
Q

Inflammatory Bowel Disease

Ulcerative Colitis and Crohn’s Disease Properties

A
25
Q

Inflammation-associated cancers

A
  • Free radicals cause DNA Damage
  • NFkB inhibits apoptosis
  • NFkB induces cell proliferation
  • Cytokines stimulate NFkB
  • Cytokines stimulate cell proliferation
26
Q
A
27
Q
A
28
Q
A
29
Q

Tissue/Pathology?

A

Foreign body Granuloma

Giant cells macrophages fusing together to try to phagocytose material

30
Q

Tissue/Pathology?

A

Foreign Body Granuloma

31
Q

Foreign Body Granulomas are?

A

Biological responses to relatively inert foreign bodies

32
Q

Foreign Body Granulomas are mediated by?

2 Listed

A
  • Macrophage mediated
  • T cells are absent
33
Q

Foreign body granulomas form around things such as?

4 Listed

A
  • Talc
  • Sutures
  • implants
  • other fibers that are too large
34
Q
A
35
Q

Tissue/Pathology?

A

Normal Aortic Wall

36
Q

Tissue/Pathology?

A

Aneurysm

37
Q

An Aneurysm is?

A
38
Q

Atherosclerosis is?

A

A Fatty streak formation - contains lipid-filled macrophages (foam cells) and activated T cells

39
Q

Fibrous cap in Atherosclerosis

3 listed

A
  • advanced stage to wall off the lesion but this can cause damage to the endothelial cells
  • the plaque can rupture and material inside plaque
  • blood clots can form
40
Q

Atherosclerosis treated by?

3 Listed

A
  • Statins
  • decrease leukocyte adhesion and NO
  • inhibits cholesterol synthsis

FMS (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions