Fluid Therapy Flashcards

1
Q

What are the indications for fluid therapy?

A
Decreased intake 
Dehydration 
Shock 
Need for overhydration 
Improve perfusion 
Correct electrolyte abnormalities
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2
Q

What are the types of shock ?

A

Hypovolemic- hemorrhage, endotoxemia, sequesteration

Vasculogenic- endotoxemia, drainage of thorax

Maldistributive- sepsis, endotoxemia

Cardiogenic - rare in horse

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3
Q

In what cases would there be a need for overhydration??

A

Liquefaction of respiratory secretions to help expectoration

Intestinal impaction —> increased flow of fluids in lumen of intestine

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4
Q

You can see increased skin tenting at what percent of dehydration ?

A

8-10%

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5
Q

Tachy mucus membranes can be seen at what percent dehydration?

A

5-7%

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6
Q

What is the primary sign that an animal is dehydrated?

A

Decreased urine output

  • will have increase USG unless there is renal involvement
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7
Q

T/F: CRT is the best indicator of dehydration

A

False

Skin tent and mm hydration are better indicators
CRT indicates perfusion (hypovolemia)

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8
Q

Sunken eyes in a horse indicate what degree of dehydration

A

12-15%

Horses only have sunken eyes in SEVERE dehydration -> imminent death is possible

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9
Q

T/F: sunken eyes in ruminants can be seen at 8-10% dehydration

A

True

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10
Q

What do you expect heart rate to be in a dehydrated patient?

A

Expect tachycardia

Can be an indicator of developing dehydration but can have many other causes

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11
Q

_________ can give overestimated impression of dehydration or can cause anemia to be underestimated

A

Spleenocontraction

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12
Q

For every 2-3% increase in percent dehydration greater than 5% dehydration, the PCV will increase ____%

A

5%

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13
Q

If your horse has a baseline PCV of 36%, and the horse is 7% dehydrated, what is the expected PCV?

A

7% - 5% dehydration = 2%
2% correlates with a 5% increase in PCV

36 + 5 = 41%

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14
Q

What is the only possible cause of hyperalbuminmeia?

A

Dehydration

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15
Q

What are clinical signs associated with hypovolemic shock?

A
Prolonged CRT (poor perfusion) 
Decreased jugular filling 
Tachycardia 
Decreased pulse pressures 
Cold extremities 
Decreased skin turgor
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16
Q

What are the major limitations of fluid administration via SQ?

A

Can’t get enough fluid in this space to make a difference in the adult horse

Rarely used in foal

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17
Q

What are the two most common methods of fluid administration in the horse?

A

PO

IV

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18
Q

What are the advantages to using PO administration of fluids?

A

Most physiologic

Inexpensive, non invasive

Especially helpful with LI impaction and overhydration techniques

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19
Q

What are the disadvantages of PO administration of fluid?

A

Contraindicated in gastric distention, reflux, and ileus

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20
Q

What are the locations for IV fluid administration in horse?

A

Jugular

Lateral thoracic - not in recumbent animals (dislodged)

Cephalic vein - easily plugs due to effect of gravity

Saphenous- typically only placed in severely depressed horses “running out” of veins to be accessed

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21
Q

What are the advantages to IV administration of fluids?

A

Easy access
Can give almost unlimited fluid

Easy adjustment of fluid plane

22
Q

Disadvantages to IV fluid administration?

A

Vein compromise -> thrombosis, thrombophlebitis, septic, phlebitis

Introduction of organisms (sepsis)

Requires aspetic technique

23
Q

When giving intra-peritoneal fluids, where do you administer?

A

Left flank.. less GI stuffs on this side

24
Q

What is the major disadvantage of intra peritoneal fluid admin?

A

Tends to tract down with abdomen causing space occupying lesion in abdomen resulting in abdominal discomfort (colic from injury or fluids?)

25
What are the advantages of rectal fluid admin?
Allow GIT absorption Can be used in severe dehydration to increased fluid if there is no jugular filling Can admin large volumes
26
When would fluids administered rectally be contraindicated ?
Severe ileus | Severe colitis
27
What is the main limitation of intraosseus fluid admin in horses?
Fluid rate limited by max needle size | 2L/hr- can be useful in foals but the adult maintenance is usually more than this
28
What are the advantages and disadvantages of intra-cecal fluid administration?
Advantage - fluid into GIT with most capacity for absorption Disadvantages - invasive, can lead to peritonitis/sepsis
29
What is the most important factor in flow rate?
Radius of catheter
30
What is the flow rate through a 14G 5.25” catheter
13.1 L/hr
31
What is the flow rate through a 14G 3.25” catheter?
14.9 L/hr
32
What is the flow rate through a 12G catheter?
26.9 L/hr
33
What is the flow rate through a 10G catheter?
36.5 L/hr
34
What is the flow rate for a STAT IV at 8’ above the horse?
28L/hr
35
When using a STAT IV set at standard 8’ ceiling, which of the following catheters will the STAT IV be the limiting factor for flow? A. 14G (5.25”) B. 14G (3.25”) C. 12G D. 10G
10G (by itself has a flow rate of 36.5L/hr) StatIV has max flow rate of 28L/hr
36
How long can polyurethane/silicone catheters stay?
Long term (up to 14days)
37
Teflon and polyethylene catheters can be left in how long?
Short term (max 72hrs)
38
What are complications due to catheters?
``` Thrombosis Cracking Breakage Air embolism Extravasation (perivascular leakage) ``` Septic phlebitis Abscessation Neurological dysfuntion Sloughing
39
What is the rate of thrombosis dependent on??
Systemic state (coagulation status): esp in state of endothelial and sepsis Stiffness, size, and length of catheter (stiff, long, and large =thrombosis) Material: polypropylene > polyethylene > teflon > silicon > nylon > polyurethane
40
What are the consequences to extravasation with catheters?
Local inflammation and pain | Secondarily leads to phlebitis and thrombophlebitis
41
T/F: Selection of appropriate fluid is dependent on expected/documented losses in the individual patient
True
42
What is the typical acid/base disturbance in a horse?
Metabolic acidosis
43
What type of solution has decreased tonicity compared to plasma?
Hypotonic solution (eg half strength saline - 0.45%)
44
What are commonly used isotonic solutions?
LRS 0.9% NaCl Normosol D5W
45
What type of solution has tonicity above plasma?
Hypertonic (7.2% NaCl)
46
Indications for using hypertonic saline??
Most strongly: emergency resuscitation in hypovolemia (hemorrhagic shock) Burn patients Acute trauma Acute neurologic trauma
47
What is the MOA of hypertonic saline?
Fluids shift from intracellular space (or 3rd space) into ECF space Trigger central brain receptor mechanism -> stimulates CNS response favoring CV stability
48
What are the effects of hypertonic saline?
Improve CO, MABP, urine production, with decrease in systemic vascular resistance. - > increase preload - > decrease afterload be decreasing endothelial cell swelling
49
What are the adverse reactions that can occur when giving horses hypertonic saline?
Hemolysis ->free hemoglobin Cardiovascular alterations -> arrhythmias ->ventricular premature contractions (VPC) With 25% HS/25% Dextran (Hypertonic first pass to the heart —> neg ionotropic)
50
Hypertonic saline decays rapidly. What can be added to prolong its effect?
6% Dextran 70
51
When is hypertonic saline contraindicated ?
Uncontrolled hemorrhage —> increased MABP and CO causes increased bleeding and CV collapse ``` Severe hypernatremia (seizure) Severe hypokalemia (promote more loss when renal fxn is restored) ```