Exercise Physiology Flashcards

1
Q

What is a measure of O2 consumption and thus athletic ability of an animal?

A

VO2 max

-measure of aerobic metabolism

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2
Q

How does VO2 max in an horse compare to catte?

A

VO2 max is 2.5x that of cattle

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3
Q

The mass of the horses heart is __________% body weight

A

0.9-1

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4
Q

Muscle accounts for ___% of body weight of equine

A

50

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5
Q

How can the horse increase O2 delivery to muscles under extreme exercise ?

A

increase HR —> increase O2 carrying capacity

Increase RBC numbers to PCV (splenocontraction)

Can reach greater O2 extraction than other species

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6
Q

What are the three major pathways for energy supply to muscles? What are the substrate?

A

Phosphocreatine

Anaerobic glycolysis - glucose / glycogen

Aerobic - carbohydrates (glycogen and glucose) and free fatty acids

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7
Q

T/F: horses have higher concentration of intramuscular glycogen and number of mitochondria/ unit muscle

A

True

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8
Q

In the first few seconds of exercise, what is the predominant pathway supplying energy?

A

Phosphocreatinine —> generates a lot of ATP but only for a short time, allows anaerobic pathway to catch up

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9
Q

What is the predominant pathway supplying energy during the first minute of exercise and during maximal exercise?

A

Anaerobic glycolysis

Process is limited by supply of glycogen in muscle and build up of lactic acidosis

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10
Q

What energy pathway is predominant in submaximal exercise and can be sustained for prolonged periods of time?

A

Aerobic

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11
Q

How are FFA used for energy??

A

Undergo beta oxidation - oxidative phosphorylation

—> makes 3x more ATP

Requires more oxygen and production is slow

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12
Q

What is the recruitment of energy systems??

A

Initially use stored ATP

At low intensity exercise, mostly aerobic metabolism

  • > glycogen stores used until 20-30% used, then switch to fat as a substrate
  • > FFA oxidation is highest at 40-60% VO2 max
  • > glycogen stores used at >60%VO2 max

High intensity

  • > use circulating glucose and glycogen stores
  • > energy increases that cannot be met by oxygen, are supplanted with anaerobic
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13
Q

What are the muscle fiber types present in horses?

A

Type I
Type IIA
Type IIX

Type I and IIa
Type IIAX

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14
Q

What are the characteristics of a type I muscle fiber?

A

Slow hydrolysis of ATP

Low glycogen content
High number of capillaries
High oxidative capacity

Not powerful
Fatigue slowly

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15
Q

The forelimb has predominantly type ____ muscle fibers

A

I

Sustain isometric force

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16
Q

What are characteristics of type IIA muscle fibers?

A

Generate force rapidly
Large number of capillaries and mitochondria
Glycolytic and oxidative mechanisms
Sustain high power for prolonged periods

17
Q

What are characteristics of type IIX muscle fibers ?

A

2x faster than IIA
High power but limited duration

Large cross sectional area, low capillaries

18
Q

What type of fibers are only recruited near maximal intensity (sprinting/jumping) and during extremely prolonged submaximal exercise ?

19
Q

What is the order of fatigue seen in muscle fibers during aerobic metabolism

A

Type I > type IIA > typeX

20
Q

T/F: Splenocontraction increases oxygen carrying capacity by increasing circulating RBC volume and increases stroke volume

21
Q

By how much can CO change in a horse doing extreme exercise ?

A

Increase from 25L/min to about 300L/min

22
Q

T/F: maximum heart rate is age dependent

A

True

Performance tends to be better in younger horses

23
Q

How is stroke volume increased during exercise?

A

Splenocontraction

Venous return enhanced by vasoconstriction, muscle contraction, and intrathoracic pressure changes

Improved myocardial contractility-> SNS

24
Q

During exercise, carotid pressures can increased from 120mmHg to 220mmHg, but the MAP does not increase by much, how??

A

Lowering of the peripheral vascular resistance by vasodilation of the muscular and cutaneous capillary beds

25
How is the minute ventilation increased during exercise in the horse??
Increase RR and tidal volume
26
How can tidal volume be increased in the horse?
Increased diaphragm contractions and intrapleural pressure changes Increased flow Visceral content acts as a pump: forelegs move forward and rib change pulled forward and outward
27
How can resistance to airflow be decreased during exercise?
High resistance in upper airways —> controlled by extension of head and of musculature results in stabilization of muscles of upper airway Cartilaginous support opposes forces of collapse associated high negative pressure
28
How can O2 extraction be increased during exercise?
Low tissue O2 increases concentration gradient, favoring off-loading Right shift dissociation curve - > hypercarbia - >high temperature - > tissue acidosis
29
What are the limitations to increasing HR and blood flow during exercise??
Excessive HR—> decreased ventricular filling Excessive flow —> decreased transit time in capillary doesnt allow for full saturation (Decreased oxygen uptake —> hypoxemia)
30
At canter and gallop stride frequency, RR rate is coupled at a ______ ratio
1:1
31
Training results in what adaptations of the CVS system?
Lower HR at submaximal exercise Increased heart mass Increases in RBC volume, Hb concentration, PV, SV muscle contraction
32
Training results in what adaptations of the musculature?
Change in fibers, hypertrophy IIX —> IIXA —> IIA —> I and IIA —> I Change in enzymatic systems: increased aerobic metabolism, change mitochondria and capillary density Modest increase in glycogen reserve