Fluid, Electrolyte, Acid-Base Balance Flashcards

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1
Q

Least hydrated tissue in body

A
  • adipose tissue
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2
Q

2 main fluid (water) compartments

A
  • intracellular fluid (ICF) 2/3
  • extracellular fluid (ECF) 1/3
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3
Q

Extracellular fluid (water) compartment

A

(1) 20% plasma (fluid portion of blood)
(2) 80% interstitial fluid (fluid in spaces between tissue cells)

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4
Q

Bonds in nonelectrolytes

A
  • covalent bonds
  • do not dissociate in solutions
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5
Q

examples of nonelectrolytes

A
  • organic molecules like glucose, lipids, creatinine and urea
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6
Q

electrolytes

A
  • dissociate into ions in water
  • can conduct electric current
  • inorganic salts, acids and bases, some proteins
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7
Q

what releases ADH

A
  • posterior pituitary
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8
Q

what releases aldosterone

A
  • adrenal cortex
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9
Q

Purpose of antidiuretic hormone

A
  • conserves water: promotes water reabsorption by collecting ducts in kidneys
  • in response to increased sodium concentration in plasma and increased ECF osmolality
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10
Q

Purpose of aldosterone

A
  • affects kidney tubules to increase Na+ reabsorption and K+ secretion
  • in response to increased K+ conc in ECF and decreased Na+ content
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11
Q

opposite effect of ADH

A
  • aldosterone
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12
Q

Influence of atrial natriuretic peptide

A
  • released in heart
  • reduces blood pressure and blood volume by inhibiting vasoconstriction, Na+ and water retention
  • makes collecting ducts reabsorb more H2O; decrease Na+ reabsorption
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13
Q

Hormone that reduces BP and BV

A
  • atrial natriuretic peptide (ANP) released by cardiac muscle cells
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14
Q

Female sex hormones and water regulation

A
  • estrogens: like aldosterone, enhance NaCl reabsorption by renal tubules
  • progesterone: decrease Na+ reabsorption
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15
Q

Hormones that enhance tubular reabsorption of Na+

A
  • aldosterone
  • estrogen (female sex hormone)
  • glucocorticoids (cortisol)
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16
Q

In response to which, is ANP released?

A
  • stretch of atria of heart due to increased blood pressure
17
Q

Which hormone regulates ECF calcium ion levels?

A
  • parathyroid hormone (PTH) stimulated by declining Ca2+ in plasma
  • promotes increase in blood calcium
18
Q

Hormone that increases blood calcium

A
  • PTH
19
Q

Which organs does PTH target?

A
  • bones, kidneys and small intestine
20
Q

How does PTH affect bones?

A
  • activate bone-digesting osteoclasts
  • osteoclasts break down the bone matrix
  • release Ca2+ and HPO4- to blood
21
Q

How does PTH affect kidneys?

A
  • increases Ca2+ reabsorption by kidney tubules/ decreases phosphate ion reabsorption
22
Q

How does PTH affect small intestine?

A
  • enhances intestinal absorption of Ca2+ by stimulating kidneys to activate vitamin D