Flaviviridae Flashcards

1
Q

Tipo de genoma

A

ssRNA positivo

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2
Q

Envueltos o desnudos

A

Envueltos

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3
Q

Cómo se transmite?

A

Por la picadura de un mosquito
- Aedes aegypti

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4
Q

Qué infecta?

A
  • Células endoteliales de capilares
  • Monocitos
  • Células dendríticas
  • Macrófagos
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5
Q

Tipos de infecciones

A
  • Líticas
  • Persistentes
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6
Q

Cómo entra a una célula?

A

Usa los receptores Fc
- Por es cada exposición se vuelve más grave

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7
Q

Cómo inicia la enfermedad

A
  • Invertebrado le pica a un animal con el virus
  • Hay viremia en el mosco
  • Mosco nos pica y su saliva nos infecta
  • Viremia (Flu-Like)
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8
Q

Chikungunya

A
  • Artritis paralizante
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9
Q

Dengue clásico

A

Clásico (Flu-like)
- Fiebre
- Cefalea
- Eritema
- Dolor de espalda
- Dolor de huesos

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10
Q

Fiebre hemorrágica (Dengue)

A

Caso grave
- Sangrado
- Choque
- Fuga capilar masiva
- Dolor abdominal (isquemia)

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11
Q

Zika

A
  • Infecta SNC y genitales
  • Exantema y fiebre
  • Bebés: Microencefalia
  • Pseudogripal en adultos
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12
Q

Fiebre amarilla

A
  • Degeneración del hígado, riñones y corazón
  • Hemorragias
  • Ictericia
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13
Q

Diagnóstico

A
  • RT-PCR
  • Anticuerpos monoclonales
  • Serología
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14
Q

Tratamiento

A
  • Vacunas atenuadas contra fiebre amarilla
  • Sintomático
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