Fitz - Managing Complications Flashcards

1
Q

AE: belomycin

A

Pulmonary fibrosis

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2
Q

AE: vinblastine

A

Neuropathy

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3
Q

AD: dicarbaxine

A

Marrow suppression

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4
Q

AE: cyclophosphamide

A

Hemorrhagic cystitis - renal toxicity

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5
Q

AE: vinchristine

A

Neurotoxicity + constipation

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6
Q

5-HT receptor agonists

A
  • odansetron
  • graisetron
  • dolasetron
  • palonsetron
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7
Q

NK1 receptor antagonist

A

Aprepitant

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8
Q

D2 receptor antagonist

A

Metoclopramide

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9
Q

Tx of high risk CINV

A
  • 5-HT
  • Aprepitant
  • dexamethazone
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10
Q

Tx of anticipatory N/V

A

Benzodiazepines

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11
Q

Moderates toxicity of HDMTX

A

Leukovorin

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12
Q

Reacts with acrolein from cyclophosphamide to diminish nephrotoxicity

A

MESNA

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13
Q

AE: doxorubicin

A

Cardiomyopathy

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14
Q

Blunts nephrotoxicity ass’d with cisplatin

A

Amifostine

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15
Q

Blunts doxorubicin cardiotoxicity

A

Dexrasoxane

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