Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuro > FINISHED Adrenergic Drugs > Flashcards

FINISHED Adrenergic Drugs Flashcards

1
Q

Phenylephrine and clonidine belong to which class of adrenergic agents?

A

Alpha receptor agonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Phenylephrine is selective for which receptor?

A

Alpha 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clonidine is selective for which receptor?

A

Alpha 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the primary therapeutic use of phenylephrine?

A

Nasal decongestant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the primary therapeutic use of clonidine?

A

Systemic hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Phentolamine and prazosin belong to which category of adrenergic agents?

A

Alpha receptor antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which alpha receptor antagonist is selective for alpha 1?

A

Prazosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which alpha receptor antagonist is non-selective for alpha 1 and alpha 2 receptors?

A

Phentolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the primary therapeutic use of prazosin?

A

Urinary retention/hesitancy and frequent urination secondary to benign prostatic hyperplasia (reduces resistance of trigone muscle of the bladder to urine outflow)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Isoproterenol and albuterol belong to which class of adrenergic drugs?

A

Beta receptor agonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which beta receptor agonist prototype is non-selective to beta 1 and beta 2 receptors?

A

Isoproterenol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which beta receptor agonist prototype has some selectivity for beta 2 receptors?

A

Albuterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the primary therapeutic use of beta receptor agonists?

A

Treatment of bronchoconstriction in patients with asthma or COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What noticeable side effect is more prominent with the use of isoproterenol as compared to albuterol in asthma therapy?

A

Tachycardia (isoproterenol also acts on beta 1 receptors in cardiac muscle)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the mechanism by which beta receptor agonists mitigate an asthma attack?

A

Beta 2 receptor activation leads to relaxation of bronchial smooth muscle, decreasing airway resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the common side effects of beta receptor agonists?

A

Cardiovascular effects, tremor, hypokalemia

17
Q

Propranolol and atenolol belong to which category of adrenergic drugs?

A

Beta receptor antagonists

18
Q

Which beta receptor antagonist prototype is non-selective for beta 1 and beta 2 receptors?

A

Propranolol

19
Q

Which beta receptor antagonist prototype is selective for beta 1 receptors?

A

Atenolol

20
Q

What is the primary therapeutic use for beta receptor antagonists?

A

Hypertension

21
Q

What are the common side effects of non-selective beta receptor antagonists?

A

Beta 2 blockade in bronchial smooth muscle, delayed recovery from insulin-induced hypoglycemia in diabetic patients.

22
Q

Amphetamine, cocaine, tyramine, and ephedrine belong to which class of adrenergic drugs?

A

Indirect-acting sympathomimetics

23
Q

What is the adrenergic mechanism of action of amphetamine?

A

Displaces norepinepherine from vesicles and increases release into the synapse through transporters

24
Q

What are the therapeutic uses of amphetamine?

A

Appetite suppression, narcolepsy, ADHD

25
Q

What is the adrenergic mechanism of action of cocaine?

A

Blocks monamine transmitter reuptake, increasing synaptic concentrations of norepinepherine

26
Q

What are the therapeutic uses of cocaine?

A

Ear, nose, and throat surgical procedures, limiting bleeding (intense vasoconstrictor effect), topical application

27
Q

What are the common side effects of cocaine?

A

Seizures, hypertensive crisis, cerebral hemorrhage, cardiac arrhythmias, myocardial ischemia

28
Q

What is the adrenergic mechanism of tyramine?

A

Causes release of catecholamines from vesicles, leading to increased synaptic concentrations of norepinepherine

29
Q

What is the primary contraindication for tyramine use?

A

Concurrent MAO inhibitor use

30
Q

What foods have high concentrations of tyramine?

A

Fermented food, some cheeses, pickled or marinated meats

31
Q

What is the adrenergic mechanism of ephedrine?

A

Mixed action: causes catecholamine release from vesicles and directly activates adrenergic receptors

32
Q

What are the therapeutic uses of ephedrine?

A

Asthma, decongestant (pseudoephedrine)

Neuro (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions