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IMSE LABORATORY > finals - viral > Flashcards

finals - viral Flashcards

1
Q

is a collection of virus coming from different families that has 1 similarities

A

hepatitis

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2
Q

size of a hepa B vius

A

42 nm enveloped virion

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3
Q

The envelope contains a protein called the _____, which is important to the laboratory diagnosis and
immunization.

A

surface antigen (HBsAg)

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4
Q

____ is the earliest serological marker that
indicate the presence of acute infection. It is also indicative of chronic infection.

A

HbsAg

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5
Q

incubation period of HIV

A

60 - 90 days

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6
Q

*The first generation tests were found on ____

A

Ouchterlony agar gel plates

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7
Q

positive result of first generational test

A

white precipitin line formed between the antigen and the antibody

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8
Q

The test was said to be not very sensitive

A

The first generation tests

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9
Q

the main similarities of hepatitis is infects the ___

A

liver

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10
Q

the hepatitis virus that has dna as its genetic material

A

hepatitis B

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11
Q

fam of hepatitis B

A

hepaDNAviridae

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12
Q

first hepatitis to be discovered

A

hepatitis B

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13
Q

who discovered Hepa B

A

Baruch Blumberg 1963

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14
Q

MOT

A

parenteral, sexual contact, perinatal (congenital)

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15
Q

hepa B is known for causing

A

liver cirrhosis
chronic liver disease

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16
Q

hepa B is known as

A

serum hepatitis

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17
Q

how to diagnose hepatitis

A

serologic (Ag and Ab)
and
molecular (confirmatory)

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18
Q

___ test determines genetic material of the virus

A

molecular

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19
Q

hepatitis B serologic markers

antigens

A

Surface - HBsAg
Core - HBcAg
envelope - HBeAg

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20
Q

hepatitis B serologic markers

antibodies

A

Anti - Hbs
Anti Hbc
Anti Hbe

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21
Q

surface marker that will determine early acute infection/chronic infection of hepatitis B

A

surface - HBsAg

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22
Q

a surface marker that can only be found in hepatocytes

A

core - HBcAg

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23
Q

surface markers - antigens - that can be found in serum

A

HBsAg
HBeAg

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24
Q

presence of antigen HBcAg means that the patient is ___

A

highly infectious

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25
a serologic marker for immunity to hepatitis -- natural immunity -- vaccinated
Anti - HBs
26
a serologic marker that will signifies past and present infection
Anti HBc --IgM --IgG
27
A presence of IgM upon confirming the presence of Anti-HbC signifies
Present infection
28
A presence of IgG upon confirming the presence of Anti-HbC signifies
Past infection
29
a serologic marker for convalescent phase which means that the patient is already in recovery period
Anti HBe
30
agent of dengue
dengue virus
31
vector for dengue
aedes aegypti aedes albopictus
32
where can we found the aedes aegypti aedes albopictus
mosquitoes in tropical areas
33
2 serological test for dengue
NS1 for antigen and IgG and IgM for antibody
34
serological test - ____ - is an immediate marker if you only got it for the first time
NS1
35
family of HIV
Retroviridae and subfamily ____
36
2 types of hiv
hiv 1 hiv 2
37
considered as a pandemic HIV
HIV 1
38
which type of HIV is more pathogenic
HIV 1
39
where can we find HIV 2?
only in africa// recent reports states that the virus mutates and has a strain outside Africa 2
40
MOT of transmission of HIV
perinatal, sexual contact, blood transfusion (blood, breast milk, vaginal fluid, csf, spinal fluid, pleural fluid)
41
stages of HIV
1. acute hiv infection 2. clinical latency 3. AIDS
42
how long will acute hiv infection takes place
2-4 weeks
43
in acute hiv infection, there will be a large amount o f___
viral
44
clinical latency stage of hiv will take how many yrs
period can last more than 10 years or decade
45
in the end of clinical latency stage of hiv, what will increase and decrease?
viral increases CD 4 cells decreases
46
last stage of HIV
AIDS
47
cd4 cells in AIDS is around
will start <200/mm3 to <40/mm3 (severe)
48
opportunistic pathogens will cause disease in this stage of HIV
AIDS
49
what is the most common opportunistic disease in AIDS
tuberculosis
50
screening test for HIV
1st gen to 5th gen
51
which generational test for HIV will use purified lysate as antigens
first gen
52
which generational test for HIV will use recombinant viral proteins
2nd gen
53
The ____ test used for HbsAg was counter electrophoresis. T
second-generation
54
in 2nd generational test, The plates were subjected to electric current. If the antigen is on the serum, a ____ would form.
fine white precipitin line
55
which generational test for HIV will use double antigen sandwich assay
3rd gen
56
which generational test for HIV will detect antibody and p24 antigen
fourth gen
57
which generational test for HIV will use multiplex assay
fifth gen
58
positive in HBsAg negative in anti HBs negative in anti HBc
early infection
59
positive in HbsAg negative in Anti Hbs positive in anti-Hbc
chronic infection
60
negative in HbsAg negative in Anti-Hbs Positive in AntiHbc
window period
61
negative in HbsAg positive in anti-Hbs positive in anti-Hbc
recovery
62
negative in HbsAg positive in Anti-Hbs negative in Anti-Hbc
vaccination

IMSE LABORATORY (8 decks)

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