FINALS: Vascular Diseases Flashcards
What is the function of the arterial system?
Brings blood rich in oxygen and nutrients from the heart throughout the body to the extremities, major organs, and tissues.
What is the function of the venous system?
Brings blood back to the heart and lungs from the tissues, organs, and extremities for waste removal and oxygen replenishment.
What is the best initial treatment for claudication?
A supervised exercise program involving walking for 30–45 minutes, 3–4x per week for 12 weeks.
What is the function of the lymphatic system?
Drains interstitial fluid from tissue spaces back into the vascular system.
What are the strongest risk factors for PVD?
Age: Risk increases with age.
Smoking: Increases risk 2–4x.
Diabetes: Increases risk, worsened by smoking.
HTN and high cholesterol: Contribute to the risk.
What is Peripheral Arterial Disease (PAD)?
A disease process affecting major arteries going to and within the extremities, often involving hardening and narrowing of the arteries, typically in the legs.
What factors affect the presentation of Peripheral Vascular Disease (PVD)?
Location of affected arteries.
Underlying cause.
Degree of narrowing/hardening.
Symptomatic vs. asymptomatic cases.
What are the common symptoms of claudication in PAD?
Mild to severe pain during exercise or exertion.
Pain reproducible with exertion and relieved by rest.
Pain may be felt in the buttock, thigh, or lower leg (most commonly calf).
What are diagnostic tests for PAD?
Ankle-Brachial Index (ABI): Screening and outcome measure.
Toe Pressure: Better for patients with diabetes.
Arterial Ultrasound: Identifies areas of narrowing or blockage.
CT Scan: Non-invasive, requires dye injection.
Angiogram: Invasive test that can guide treatment.
What is rest pain in PVD?
ersistent pain, often in feet and toes, worse at night or with leg elevation, relieved by dangling the leg downward.
What are key recommendations for asymptomatic PVD patients?
Quit smoking.
Increase activity and exercise.
Control blood pressure and blood sugar.
Improve nutrition.
Reduce inflammation.
What is the prognosis for asymptomatic PVD patients?
4–11% progress to symptomatic disease in 5 years.
Less than 1% per year risk losing a leg.
Most patients with claudication will not significantly worsen.
What interventions are recommended for severe PVD?
Endovascular repair.
Open surgery.
Treatment based on blockage location and extent.
Rheumatoid Vasculitis: ?
Cryoglobulinemia: ?
Polyarteritis Nodosa (PAN): ?
Rheumatoid Vasculitis: Severe RA complication.
Cryoglobulinemia: Linked to hepatitis C.
Polyarteritis Nodosa (PAN): Necrotizing vasculitis with systemic involvement.
Upper Extremity Ischemia
Key Features: Rare compared to lower extremities, with vasospasm as a common cause.
Symptoms: Coldness, color changes, ischemia, and severe cases leading to ulcers or gangrene.
Common Conditions: Raynaud’s Phenomenon, Buerger’s Disease, vasculitis, frostbite, occupational trauma.
Notable Sites:
Ulnar Artery: Often asymptomatic due to collateral circulation.
Axillary Artery: Severe ischemia when obstructed.