FINALS QUIZ 1

Question 1

The oxidation of iodide and coupling reaction is catalyzed by?

Answer 1

Thyroid Peroxidase

Question 2

What is the functional unit of the thyroid gland?

Answer 2

Follicle

Question 3

What hormone is synthesized by the parafollicular cells?

Answer 3

Calcitonin

Question 4

Thyroglobulin is synthesized on what part of the follicular cell?

Answer 4

Rough Endoplasmic Reticulum

Question 5

The NIS (Sodium Iodide Simporter) activity is regulated by what hormone

Answer 5

Thyroid Stimulation Hormone

Question 6

What chemical oxidizes iodide into iodine?

Answer 6

Hydrogen Peroxide

Question 7

The coupling of two DIT produces what

Answer 7

Thyroxine/Tetraiodothyronine

Question 8

What type of endocytosis is employed during the uptake of thyroglobulin from the colloid to the follicular cells

Answer 8

Pinocytosis

Question 9

What organelle takes up the thyroglobulin upon entering the follicular cell from the colloid?

Answer 9

Lysosomes

Question 10

What is the half life of T4

Answer 10

8 days

Question 11

What is the carrier protein that only carries T4

Answer 11

Transthyretin

Question 12

The production of rt3 is catalyzed by

Answer 12

5-deiodinase

Question 13

Other name of T3 thyrotoxicosis

Answer 13

Plummer’s Disease

Question 14

What autoimmune disorder is caused by thyroid stimulating immunoglobulins?

Answer 14

Grave’s Disease

Question 15

A condition in which the FT4 and FT3 is normal but the TSH is low

Answer 15

Subclinical hyperthyroidism

Question 16

Enumerate at least 3 symptoms of Hyperthyroidism

Answer 16

• Heat Intolerance
• Tachycardia
• Weight Loss
• Tremor