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MICROBIOLOGY MED2 > Finals: Integrative > Flashcards

Finals: Integrative Flashcards

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1
Q

Dengue diagnostic test/s for acute phase (<5 days after fever onset)

A

DENV specimen PCR
Nonstructural protein 1 (NS1) assays

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2
Q

CBC lab test is requested for dengue around which day after fever onset?

A

4th or 5th day
when WBC decreases (neutropenia), platelet decreases while hematocrit increases

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3
Q

What dengue test is requested at 5 days or more after the onset of fever?

A

IgM anti-DENV enzyme-linked immunosorbent assay (MAC ELISA)

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4
Q

Major class of immunoglobulin found in the serum

A

IgG

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5
Q

Longest half-life among the Ig classes

A

IgG

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6
Q

Most efficiet immunogloculin in agglutination, complement fixation, and other antugen-antibidy reactions as it is secreted as a pentamer

A

IgM

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7
Q

Major Ig responsible for mucosal immunity

A

IgA

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8
Q

In mucous secretions, IgA is a dimer and referred to as:

A

secretory IgA

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9
Q

Ig that has an additional constant region (CH4)

A

IgE

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10
Q

This is the major surface bound Ig on mature B lymphocytes that have not yet encountered an antigen

A

IgD

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11
Q

These 2 Immunoglobulins are the only isotype that can be expressed together by the same cell

A

IgD and IgM

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12
Q

Common name for dermatophytosis

A

Ring worm (tineas)

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13
Q

Dermatophyte that only infects the skin and nails

A

Epidermophyton

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14
Q

Dermatophyte that only infects the skin and hair

A

Microsporum

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15
Q

True or false: Dermatophytes are resistant to cycloheximide

A

True

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15
Q

True or false: Dermatophytes are resistant to cycloheximide

A

True

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16
Q

The several dermatophytic species that are capable of sexual reproduction produce ____________ and belong to the teleomorphic genus __________.

A

ascospores
Arthroderma

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17
Q

If a fragment of chromosomal DNA has been incorporated into the plasmid, it is designated as an:

A

F’ plasmid

18
Q

If F plasmid sequence is integrated into the bacterial chromosome, the cell is designated an:

A

Hfr (High frequency recombination) cell

19
Q

DOC for Sporotrichosis

A

Itraconazole

20
Q

Guarnieri bodies areintracytoplasmic finding in infections caused by:

A

Variola or small pox

21
Q

Cowdry type A in Tzanck smear is seen in which infection?

A

Herpes Simplex Virus [2?]

22
Q

A dense central, ‘‘owl’s eye,” basophilic inctranuclear inclusion body is the histologic hallmark of which infection?

A

Cytomegalovirus

23
Q

Which genera of herpesvirdae are classified under betaherpes?

A

Cytomegalovirus and Roseolovirus

24
Q

Latent infection of virus from Rhadinovirus genus is found in:

A

Lymphoid tissue

Rhadinovirus is HHV 8 (Kaposi’s sarcoma-associated herpesvirus)

25
Q

The genus Lymphocryptovirus is classified under which subfamily of Herpesviridae?

A

Gammaherpes (with Rhadinovirus)

26
Q

Latent infections of HHV 5 are found in:

A

glands and kidneys

HHV 5 is CMV under the betaherpes subfamily

27
Q

This cytopathological finding distinguish HSV & VZV from Coxsackievirus

A

Multinucleated Giant cells (syncytia formation)

28
Q

T/F: Serology is useful in the diagnosis of HSV

A

F:
Serology is not useful for HSV diagnosis except for epidemiology

29
Q

Drug of Choice for HSV

A

Acyclovir

30
Q

The most important criterion for the recognition of Staphylococcus species

A

Coagulase production

31
Q

Test used to identify Streptococcus pneumonia (susceptible) as this reveals “No zone of inhibition” around the disk among other viridans group strep

A

Optochin test

32
Q

Tetanospasmin blocks the release of which inhibitory transmitters?

A

glycine and GABA

33
Q

Type of conidia seen in aspergilloma

A

Phialoconidia

34
Q

Aspergillus species that is the most common cause of invasive and chronic aspergillosis

A

A. fumigatus

35
Q

Aspergillus species that causes invasive infection primarily in patients with chronic granulomatous disease

A

A. nidulans

36
Q

Opportunistic fungi that peoduce aerial hyphae that bear conidial structures and long conidiophores with terminal vesicles

A

Aspergillus

37
Q

What are the primary risk factors for invasive aspergillosis?

A

Profound neutropenia and glucocorticoid use

38
Q

A mycetoma caused by a bacteria

A

Actinomycetoma

39
Q

A definitive pathologic diagnosis of rabies can be based on the finding of ________________ in the brain or the spinal cord. They are sharply demarcated, more or less spherical, and 2–10 µm in diameter, and they have a distinctive internal structure with basophilic granules in an eosinophilic matrix.

A

Negri bodies

40
Q

Sugars in TSI

A

Glucose
Lactose
Sucrose

41
Q

This E. coli will have negative (clear colonies) on sorbitol MacConkey agar (sorbitol is used instead of lactose)

A

STEC O157:H7

42
Q

Selective media for vibrio

A

Thiosulfate-citrate-bile-sucrose agar

MICROBIOLOGY MED2 (9 decks)

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