FINALS: EXTRAINTESTINAL CESTODES Flashcards
“Dog tapeworm/hydatid tapeworm”
Shortest tapeworm
Zoonotic disease
Adult worms inhabit the small
intestines of canines
Unilocular hydatid cyst
Accidental host – humans
Echinococcus granulosus
Identical to Taenia
Accidentally ingested by humans
Echinococcus granulosus OVA
Larval stage
Diagnostic stage
Found in human tissues
Unilocular/granular
1-7cm in diameter and grows 1-5cm in
diameter per year
Protoscolices may be found in brood
capsules, which contain only the
germinal layer, and daughter cysts
which are replicas of the mother cysts
Brood capsules
o Rupture and release protoscolices
Hydatid sand
o Protoscolices and brood capsules that lie free in the cysts
Echinococcus granulosus HYDATID CYST
is a parasite larvae that
develop into adult worm; before pa
maging scolex
Up to 2 million
Protoscolices
Echinococcus granulosus DH?
DOGS
Echinococcus granulosus IH?
- GOAT
- HORSE
- CAMEL
- SHEEP
o Caused by developing
larval cyst in tissues
o Ingestion of
embryonated eggs
o Involvement:
Liver –
common site
Lungs
Brain
Orbit
Cyst may rupture (CAN CAUSE METASTASIS) through coughing, muscle strain, trauma, aspiration, operative procedure
- o May cause metastasis
and will develop into
secondary cysts within
2-8 years
Human cystic echinococcosis
Allergic symptoms/anaphylaxis LIVER?
JAUNDICE
Allergic symptoms/anaphylaxis BRAIN??
EPILEPSY
Allergic symptoms/anaphylaxis KIDNEY?
HEMATURIA AND KIDNEY DYSFUNCTION
Examination of hydatid cyst
o Radiography
o Ultrasonography
Serologic tests
o Indirect Hemagglutination (IHA)
o Indirect Fluorescence Antibody (IFA)
o Enzyme Immunoassays (EIA)
o Can result to false-positive findings
o Intradermal/skin test
Casoni (INTRADERMAL SKIN) test
o Produced during infection
Anti – P1 antibodies
Small (<7cm in diameter)
- ALBENDAZOLE
- MEBENDAZOLE
Large (>10cm in diameter)
Surgical resection
Multiple cyst
o PAIR
Percutaneous puncture
Aspiration of cystic fluid
Injection of protoscolicidal agent
(e.g., 95% ethanol or
hypertonic saline) for
at least 15 minutes
Re-aspiration
“Fox tapeworm”
Zoonotic, similar structure with E.
granulosus
Multiocular/alveolar cysts
Definitive host – foxes
Intermediate host – rodents
Echinococcus multiocularis
the cyst that can be for in Echinococcus multiocularis
Multiocular/alveolar cysts
Multiocular/alveolar cysts can cause>?
ALVEOLAR ECHINOCOCCOSIS
Under the order Pseudophyllidean
Human involved:
o Spirometra mansoni
o Spirometra erinacei
o Spirometra ranarum
SPIROMETRA SPP.
Ingested by 1st IH
CORACIDIUM
o In 1st IH
Procercoid
o Aka sparganum
o In 2nd IH
Plerocercoid
Intermediate hosts S. spp
o 1st: Copepods
Cyclops
o 2nd
Frogs, snakes,
chickens, fish
SPIROMETRA SPP. DH?
DOGS AND CATS
SPIROMETRA SPP. PARATENIC HOST
WILD PIGS
o Larval infection specifically the plerocercoid larvae
o Infection via:
Drinking water containing Cyclops and copepods infected with procercoid larvae
Eating 2nd IH infected
with plerocercoid
larvae
Applying plerocercoid
infected flesh of frogs
and snakes as poultices on sores on the eye, vagina, and skin resulting in subsequent penetration into cutaneous tissues
Consumption of paratenic hosts
Sparganosis
TREATMENT FOR S. SPP?
Surgical removal of larvae – main form of treatment
Praziquantel is also recommended but the efficacy is not yet proven
S. SPP Plerocercoid larvae can live up
20 YEARS
o Sparganum can be found in any part of the body
Migrating tumor:
Painful edema
due to larvae migration
o Local infection cause
Urticaria, erythema, chills, fever,
IDENTIFY:
Rostellum: unarmed
Segments (gravid proglottids): spiral
uterus
Length: similar but shorter than D.
latum
Eggs: operculated and immature
similar to D. latum
Spirometra spp.
IDENTIFY:
Scolex: pyriform with short neck with
four acetabula
Rostellum: 30-36 hooks
Length: 3-6mm
Strobila: three proglottids - immature,
mature, and gravid (widest and
longest)
Echinococcus granulosus