FINAL TEST!! Antibiotics Flashcards
Penicillin G is blank and three forms
Bactericidal
Benzathine
Potassium
Procraine
Lins are category what for preg?
B
PBP inhibitors 4 and all of the cell wall inhibitors add one more
Pen B, Ampicillin, Cefazolin, Primaxin,
and vancomycin
Pen G Tx 4
Gram Positive- Staph, strep, bacterial endocarditis. recurring rheumatic fever. Narrow spectrum
Pen G Adverse effects 3 that all flow into each other
Usually tolerated well Itching-hypersensitivity or anaphylaxis.
Oral contraceptives, ahminoglycosides should not be taken with what drugs?
Pen and AMP
Aminoglycosides can be blocked when taking pen and need to be given a few hours apart.
Ampicillin Trx.3 and spectrum
Ear infections respiratory infections and E.Coli Broad spectrum
Ampicillin adverse effects 2 easy
GI upset, rash,
One nursing consideration with AMP
Food can block absorption give on an empty stomach
Cefazolin is a what class what gen what spectrum?
Cephalosporin 1st gen Broad.
Cefazolin Trx
Gram positive res, uti, skin, prophylactic for surgery,
Cefazolin nursing considerations 2
Use cautiously with patients with sensitivity to PCN and increased risk of nephrotoxicity especially with aminogly and vanco
Primaxin preg class and trx and what that means
C complicated infections resistant type infections gram pos and neg an and ae it means it is broad
Primaxin nursing considerations 2
Make sure kidneys are ok Combined to make sure high levels stay in the blood stream
Vancomycin used for and MA
severe infections, c.diff. and MRSA Cell wall destruction and RNA interference
VAnco Adverse effects 4
Red man syndrom-flushed tachy, hypo, rash upper body
Phelbitis/necrosis
Otoxicity
nephrotoxicity
Anti infective protein synth 3
tetracycline, erythromycin, Garamycin
tetracycline trx and is considered blank and blank and category blank
H.pylori, sever acne bacteriostatic ver broad spectrum D.
tetracycline adverse effects
Gastric irritation, Esoph irritation, teeth staining, superinfections, photosensitivity, diarrhea
tetra nursing considerations 3 all stomach
Take on empty stomach
Difficult to balance GI distress and food intake
Minoand doxy can be taken with food
Erthromycin 3 things
Bacteriostatic, good for people with allergies to pen, Zpack-long half life so less dosing
Erythro AE 3
N/V ab pain
Phlebitis
inhibits P45- enzymes
Nursing consideration for Eryth
Grapefruit juice increases drug level
Gentamicin is a what and what preg class? two other things spectrum and when to use?
Aminoglycoside D Narrow spectrum and last resort
Gentamicin AE 4
Neurotox, Ototox, parastehsias-mm twitching, Nephrotox, neuro dysfunction.
Nursing considerations for Gentamicin 3
Given IV because poorly absorbed in GI
Monitor bun and creatin
Give separate from Pen
Fungizone 4 Spectrum preg systemic or local class
Broad spectrum
preg B
Systemic
Poyene
MA antifungals
Bind to ergosterol (Steroid that constructs plasma in membrane)
Fungizone AE 6 with 1 BBW
Nephrotoxicity, fever/chills, Anorexia, HA, ototoxicity.
BBW-cardiac issues blood abnormalities.
Don’t give fungizone with…
Fluconazole
Fluconazole Spectrum preg 2 special class
Broad
candida/ less toxic than fungizone
C
Azole
Nursing consideration for fungizone Route how?-why? How long? Monitor?
Give IV- GI no absorption infuse too quickly and will cause hypokalemia
treat for a long time
monitor kidneys
Nyastatin
Route
preg
trx
PO
B
Folds of skin yeast
Nyastatin AE
Skin irritation/burning
toxic if given systemically
Nyastatin nursing consideration 1
Not for systemic
Bactrim MA
used for 4
Nursing Cat and what it effects
class
Inhibits synth of folic Acid Acute uncomplicated and complicated UTIs Pneumonia, bronch, diarrhea C-crosses placenta/BM Sulfonamide
Bactrim AE 5
Steven johnsons syndrom
Pruritus-itch, rash, photosensitivity, renal damage from crystals.
Macrobid
Class-
Preg
UT antiseptic
B
Macrobid AE
so becareful with
H/a and N/V
pulmonary toxicity
hepatotoxicity
Previous lung/liver problems
Cipro MA Class Spectrum TRX-5
Fluoroquinolone
Inhib DNA replication
Broad
UTI, skin, resp, sinus, bone, eye
Cipro BBW and AE -Easy 3
Tendon
N/V/D
3 considerations of cipro
Admin vit/min sep
adults 18 plus ok
Cat-ions and dairy- Be careful
Combination Chemo Drugs 3 things
Drug needs to be effective by its self
2nd drug needs to have different MA
Min overlap toxicity