Endocrine Flashcards
Glucagon
hormone that increases blood glucose levels.
Glycogenolysis
Glycogen broken down to release glucose into the blood steam
glycogenesis
production of glucose from non-carbohydrate sources (amino acids)
high blood sugar effects
the heart and the kidneys
Type one
What is it?
percent?
onset?
no insulin available destruction of beta cells in the pancreas. 5-10 percent of diabetes
Abrupt childhood or youngadult
Type 2-
Type 2- cells are not responding to insulin 90-95 percent of people. people tend to have obesity high blood pressure onset middle age
Gestational diabetes-
glucose intol during preg. Usually temp. There is a risk that they might develop after. Treated with insulin. It will effect mom and baby. Once baby is born there is hypoglycemia in the mom high birth weight for the baby.
Lab values-
Fasting plasma glucose 126mg/dL after fasting 8 hours=diabetes
Normal glucose is 60-100mg/dL
HbA1C-measures prolonged hyperglycemia- the amt of glucose bound to hemoglobin (Hgb) (ave measure over 2-3 months). >6.5%
Prediabetes-100-125mg/dl
Treatment type 1
Insulin therapy
Treatment 2
anti-diabetic drugs and sometimes insulin-many times needed later on for continued tight control of blood sugar. Diet
Exercise-
Medications- oral ani-diabetic drugs+ Insulin
thyroid effects
Metabolism
GI function
Cardiac function
Growth and development
T Hormones
synthesized from iodine and aminoacidic tirozine
-Tri-iodothyronine (T3)
Thyroxine (T4)
-Majority of circulating hormone is in the T4 but once it enters the peripheral tissues, it converts to T3 (bio active form of hormone)
Regulated by hypothalamus and anterior pituitary gland-Negative feedback loop.
Learn thyroid hormone feedback loop
ok?
Hypothyroidism causes
Autoimmune thyroiditis (hashimotos thyroiditis)
-Most common
Destruction of thyroid by radioactive iodine
Insufficient dietary iodine
-not common in USA because of salt
Surgical removal if thyroid
Hyperthyroidism
Graves disease-autoimmune disorder
Excess thyroid hormone- goiter, exothelium’s bulging eyes.