final review Flashcards

1
Q

TMPRSS2-ERG gene is associated with

A

prostatic adenocarcinoma

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2
Q

isochromosome 12- i(12p) is associated with

A

testicular carcinoma- classic seminoma

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3
Q

BPH is located _____ in the prostate

A

centrally

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4
Q

Carcinoma is located ____ in the prostate

A

peripherally

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5
Q

genetic/cytogenetic abnormality:

p53 mutation

A

serous CA of endometrium (Type 2 endometrial carcinoma)

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6
Q

genetic/cytogenetic abnormality:

69XXY

A

partial mole

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7
Q

genetic/cytogenetic abnormality:

46XX (all paternal chromosomes)

A

complete mole

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8
Q

Isochromosome 12p or extra 12p is highly specific for germ cell tumors; extra copies of 12p associated with tumor progression and treatment failure, particularly in non-seminomatous germ cell tumors

A

yep

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9
Q

genetic/cytogenetic abnormality:

PTEN

A

hyperplasia- type 2 endometrial cancer

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10
Q

carcinoma associated with DES exposure in utero

A

clear cell adenocarcinoma of vagina

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11
Q

cancer associated with the vagina; small round blue cell tumor and it is desmin positive

A

embryonal rhabdomyosarcoma

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12
Q

most frequent cause of death in untreated squamous cell carcinoma of the cervix

A

renal failure due to ureteric obstruction, hydroureter and hydronephrosis

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13
Q

most common invasive malignancy of the female reproductive tract is cancer of the

A

endometrium

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14
Q

Meig syndrome is the association of ascites and hydrothorax with an ovarian tumor, usually:

A

fibroma

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15
Q

krukenberg

A

metastatic

**stomach/colon/breast cancer

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16
Q

sertoli-leydig ovary neoplasm releases

A

androgen

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17
Q

schiller-Duval- glomeruloid body

A

Yolk sac

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18
Q

call-exner or coffee bean nucleus

A

granulosa/estrogen cell tumor

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19
Q

word associations:

HCG

A

choriocarcinoma

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20
Q

word associations:

AFP

A

Yolk sac

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21
Q

word associations:

CA 125

A

serous adenocarcinoma

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22
Q

word associations:

serotonin

A

carcinoid

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23
Q

word associations:

thryoid hormone

A

struma ovarii

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24
Q

word associations:

endometriosis

A

endometrioid and clear cell CA endometriotic cyst

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25
Q

word associations:

fallopian tube STIC

A

serous tubal intraepithelial carcinoma- serous carcinoma of ovary

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26
Q

word associations:

psammoma bodies

A

serous carcinoma- papillary tumor

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27
Q

word associations:

LDH

A

dysgerminoma/seminoma

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28
Q

When do we see human placental lactogen

A

early pregnancy

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29
Q

acetylcholinesterase is associated with

A

neural tube defect- AFP

30
Q

magnesium sulfate is a

A

calcium antagonists and thus it is a uterine relaxants

31
Q

what acts as ripening agents

A

prostaglandins

32
Q

acceleration- deceleration-acceleration is due to compression and decompression of the cord

A

variable decelerations

variable deceleration are variable in duration, intensity and timing.

33
Q

severe decelerations have depth below 70 bpm, and a duration longer than 1 minute.

persistent variable decelerations may lead to acidosis and fetal distress

A

severe variable decelerations

34
Q

fetal heart rate lags behind contractions, with little or no vriability in line.

Persistent late decelerations associated with decreased variability is an ominous pattern

A

late deceleration with variability loss

35
Q

baseline fetal heart rate is 120-160, preserved beat to beat and long term variability

accelerations last for 15 or more seconds above baseline, and peak to 15 or more bpm

A

reassuring pattern

36
Q

what is the risk of breast carcinoma from a fibroadenoma

A

no risk- completely benign

37
Q

BRACA has what percentage of getting breast carcinoma

A

60-85% lifetime risk

38
Q

These are all:

Adenosis
Apocrine metaplasia
Duct ectasia
Ductal hyperplasia of usual type, mild

A

benign, non-proliferative disease that have no increased risk of developing breast carcinoma

39
Q

these are all:

Ductal hyperplasia of usual type, moderate or florid
Intraductal papilloma
Sclerosing adenosis

A

benign proliferative disease without atypia have a slight increase risk of developing breast carcinoma

40
Q

breast carcinoma risk from atypical ductal hyperplasia

A

moderate risk

41
Q

breast carcinoma risk from DCIS and LCIS

A

high risk

42
Q

Foci of chronic inflammatory cells in the stroma and normal appearing glands

A

prostatitis

43
Q

Glands lined by a single layer of epithelium and packed back to back

A

prostatic adenocarcinoma

44
Q

Hyperplastic nodules of stroma and glands lined by two layers of epithelium

A

BPH

45
Q

Nests of cells with glycogen rich cytoplasm and prominent nucleoli with lost of lymphocytes

A

classic seminoma

46
Q

menorrhagia and pelvic pain with no nodularity but symmetrically enlarged uterus

A

adenomyosis

47
Q

Under the influence of high levels of unopposed estrogen, the endometrium undergoes hyperplasia.

Glands&raquo_space;» stroma

A

endometrial hyperplasia

48
Q

leiomyomas are estrogen and progesterone sensitive?

A

yep, may regress if estrogen decreases or increase in size in pregnancy

49
Q

deformity that leads to torsion of testes

A

bell clapper

50
Q

Clomiphene citrate is a

A

selective estrogen receptor modulator and is used for ovulation induction.

51
Q

Letrozole is an

A

aromatase inhibitor and also used for OI.

52
Q

pituitary infarction due to postpartum hemorrhage

A

sheehan syndrome

53
Q

string of pearls sign

A

PCOs

54
Q

endometrial hyperplasia without atypia

A

progesterone only medication

55
Q

cervical cancer is treated by

A

radical hysterectomy

56
Q

Boobs-pubs-spurts-squirts

A

female puberty timing

57
Q

atony

A

uterus does not contract after labor

58
Q

matrix metalloproteinase

A

it is a collagen bond disruption which allows to ripen the cervix

59
Q

hyaluronic acid

A

increases in hydration of ground substance

60
Q

which is the main hormone for cervical ripening

A

prostaglandins

61
Q

transverse lie needs to be delivered by

A

Cesarean C-section

62
Q

station AP view

A

baby location based on ischial line

+2 +3- very low stations

63
Q

progesterone does what?

A

relaxes smooth muscle

64
Q

blood pressure in pregnancy?

A

is decreased due to progesterone mediated decreases in peripheral vascular resistance

65
Q

cystocele

A

prolapse of the bladder

66
Q

enterocele

A

prolapse of the small bowel

67
Q

rectocele

A

prolapse of the rectum (hernia)

68
Q

uterine prolapse

A

prolapse of the uterus

69
Q

vaginal vault prolapse

A

prolapse of the vagina- after a hysterectomy

70
Q

fetal insuffiiciency/ fetal hypoxia fetal monitor patterns

A

late decelerations with variability loss