final review Flashcards
TMPRSS2-ERG gene is associated with
prostatic adenocarcinoma
isochromosome 12- i(12p) is associated with
testicular carcinoma- classic seminoma
BPH is located _____ in the prostate
centrally
Carcinoma is located ____ in the prostate
peripherally
genetic/cytogenetic abnormality:
p53 mutation
serous CA of endometrium (Type 2 endometrial carcinoma)
genetic/cytogenetic abnormality:
69XXY
partial mole
genetic/cytogenetic abnormality:
46XX (all paternal chromosomes)
complete mole
Isochromosome 12p or extra 12p is highly specific for germ cell tumors; extra copies of 12p associated with tumor progression and treatment failure, particularly in non-seminomatous germ cell tumors
yep
genetic/cytogenetic abnormality:
PTEN
hyperplasia- type 2 endometrial cancer
carcinoma associated with DES exposure in utero
clear cell adenocarcinoma of vagina
cancer associated with the vagina; small round blue cell tumor and it is desmin positive
embryonal rhabdomyosarcoma
most frequent cause of death in untreated squamous cell carcinoma of the cervix
renal failure due to ureteric obstruction, hydroureter and hydronephrosis
most common invasive malignancy of the female reproductive tract is cancer of the
endometrium
Meig syndrome is the association of ascites and hydrothorax with an ovarian tumor, usually:
fibroma
krukenberg
metastatic
**stomach/colon/breast cancer
sertoli-leydig ovary neoplasm releases
androgen
schiller-Duval- glomeruloid body
Yolk sac
call-exner or coffee bean nucleus
granulosa/estrogen cell tumor
word associations:
HCG
choriocarcinoma
word associations:
AFP
Yolk sac
word associations:
CA 125
serous adenocarcinoma
word associations:
serotonin
carcinoid
word associations:
thryoid hormone
struma ovarii
word associations:
endometriosis
endometrioid and clear cell CA endometriotic cyst
word associations:
fallopian tube STIC
serous tubal intraepithelial carcinoma- serous carcinoma of ovary
word associations:
psammoma bodies
serous carcinoma- papillary tumor
word associations:
LDH
dysgerminoma/seminoma
When do we see human placental lactogen
early pregnancy