Final Review Flashcards
Which of the following is NOT an example of an exocrine gland?
a.ovary cells that secrete estrogen into the blood
b. sweat gland that secretes onto the skin
c. ovaries secreting an egg into the fallopian tube
d. salivary gland that secretes into the mouth
a.ovary cells that secrete estrogen into the blood
The Na+/K+ pump transports _____ the cell and _____ the cell per cycle.
2 K+ into; 3 Na+ out
How much of the total body water content is in the intracellular compartment?
67%
The entire epidermis is replaced every
2 weeks.
T/F
An integrating center of a negative feedback loop has the function of analyzing information from sensors about deviations from a set point and then altering the activity of particular effectors to compensate for the deviation.
true
_____ is the transport of digestion products across epithelium into blood.
absorption
_____ trials involve testing the drug on healthy humans.
Phase I clinical
T/F
Facilitated diffusion is unable to transport molecules against a concentration gradient.
true
t/f
Active transport proteins are often regulated by phosphorylation.
true
The zygote (fertilized egg) before implantation has the ability to produce all the various types of cells found in the body. This ability is known as being _____.
totipotent
Contraction of _____ muscle can be consciously controlled.
skeletal
Which of the following is NOT a primary tissue of the body?
a.adipose
b. nervous
c. epithelial
d. connective
adipose
The rate of diffusion is influenced by
a.the concentration gradient.
b. membrane permeability.
c. membrane surface area.
d. membrane thickness.
e. all of the above
all of the above
Channels present in the membranes of some cells that allow rapid movement of water are called _____.
aquaporins
Thermoregulation directly involves:
a.eccrine sweat glands.
b. sebaceous glands.
c. apocrine sweat glands.
d. lacrimal glands.
eccrine sweat glands.
t/f
Bacteria are responsible for the characteristic body odor of apocrine sweat.
true
Which of the following organ’s cells do NOT have many aquaporins in their plasma membranes?
a.brain
b. salivary glands
c. skin
d. eyes
e. lungs
f. kidneys
skin
What type of muscle tissue would you expect to find associated with blood vessels?
smooth
The part of a neuron that is typically lined with myelin sheath and transmits electrical impulses toward the synapse is called the _____.
axon
Which physiologist is known for showing that the heart pumps blood through a closed system?
a.Claude Bernard
b. Walter Cannon
c. Karl Landsteiner
d. William Harvey
William Harvey
_____ transport directly requires ATP.
Active
Why are cells in body organs generally within 100μm if a blood capillary?
a.to decrease mean diffusion time
b. so that larger particles can diffuse more easily
c. to increase mean diffusion time
d. a larger distance maximizes entropy
to decrease mean diffusion time
What physiologist is known for coining the term homeostasis to describe the dynamic constancy of the body’s internal environment?
a.Claude Bernard
b. Walter Cannon
c. Karl Landsteiner
d. William Harvey
Walter Cannon
Proteins that extend from the cytoskeleton within the cell, through the plasma membrane, and into the extracellular matrix are _____. These structures affect cell motility, adhesion, and proliferation.
integrins
Which glucose carrier is found in skeletal muscle and activated by either insulin or exercise?
a.GLUT1
b. GLUT2
c. GLUT3
d. GLUT4
d.GLUT4
T/F
Most organs are comprised of groupings of the four primary tissues into structural and functional units.
true
The cell membrane is typically most permeable to _____ ions.
potassium
Cerebral edema (swelling of the brain caused by excess fluid) would be treated with a(n) _____ intravenous solution of mannitol.
hypertonic
Which of the following is NOT true of a person who is dehydrated?
a. increased osmolality causes thirst
b. hypothalamus stimulates release of ADH from the pituitary gland
c. plasma osmolality increases
d. ADH causes the kidneys to excrete water
d.ADH causes the kidneys to excrete water
T/F
Phase IV clinical drug trials involve testing a drug only on the specific human population who have the condition that the drug is intended to treat.
true
I give a patient an IV drip of a 0.8 Osm solution. How would you expect the patients red blood cells to react once this solution enters their veins?
a. The cells will not change.
b. The cells will swell.
c. The cells will crenate.
d. The cells will lyse.
c.The cells will crenate.
Which of the following is NOT a type of junctional complex?
a.Macula occludens
b. Zonula adherens
c. Zonula occludens
d. Macula adherens
a.Macula occludens
The last name of the physiologist who performed work on the physiology of digestion is _____.
Pavlov
The study of how disease or injury alters physiological processes is termed
pathophysiology
Which type of connective tissue is characterized by a liquid extracellular matrix?
blood
Botulism ends up resulting in death because it alters _____, the protein complex responsible for docking synaptic vesicles to the plasma membrane of the terminal bouton.
SNARE
The functional connection between a neuron and a second cell is called the _____.
synapse
During the _____ refractory period, a supramaximal stimulus can bring the cell to threshold.
relative
Electrical synapses occur via _____ _____ and are found in both smooth and cardiac muscle as well as between some neurons of the brain and between neuroglial cells.
gap junctions
T/F
An axon will depolarize only if the membrane potential reaches the threshold value.
true
Parkinson’s disease is difficult to treat because it results from a deficiency of dopamine in the brain and giving an individual dopamine, unfortunately, has no impact on the disorder. This is because dopamine cannot cross the _____ _____ _____.
blood brain barrier
Using a stronger stimulus to activate more neurons in a nerve is called _____.
recruitment
What happens to prevent a new action potential from starting during the absolute refractory period?
a. A polypeptide blocks the potassium voltage-gated channels.
b. Depolarization opens the calcium voltage-gated channels.
c. A polypeptide blocks the calcium voltage-gated channels.
d. Depolarization opens the potassium voltage-gated channels.
e. Depolarization opens the sodium voltage-gated channels.
f. A polypeptide blocks the sodium voltage-gated channels.
f.A polypeptide blocks the sodium voltage-gated channels.
The pineal gland releasing melatonin into your bloodstream is an example of _____ signaling.
endocrine
Why is the plasma membrane more permeable to potassium than any other ion?
a. There are leaky potassium channels that are not-gated and allow potassium through the membrane all the time.
b. There are voltage-gated channels for potassium that open in response to stimuli.
c. There are ligand-gated channels for potassium that open during depolarization.
d. a and b
e. b and c
f. a and c
g. a, b, and c
d.a and b
Action potential transmission in the PNS is decreased if _____ cells are damaged.
Schwann
Which G-protein subunit binds GDP?
alpha
If axons are myelinated they appear to be _____ in color.
white
Using a stronger stimulus will cause which of the following to increase?
action potiental frequency
What is the term for a bundle of axons located outside the central nervous system?
nerve
What voltage-gated channels are present in the axonal membrane at the terminal bouton?
a. Sodium
b. Potassium
c. Calcium
d. a and b
e. b and c
f. a and c
g. a, b, and c
g.a, b, and c
Which neuroglial cell of the CNS lines the brain ventricles and spinal cord and is responsible for producing cerebrospinal fluid?
ependymal cells
Which neuroglial cell of the CNS phagocytizes foreign and degenerated material when active?
microglia
Which is NOT a function of astrocytes?
- phagocytize foreign material
- formation of the blood-brain barrier
- take up excess neurotransmitters
- take up extracellular K+
- release gliotransmitters
- takes up glucose to produce lactic acid or lactate
- synapse formation, maturation, and maintenance
- release prostaglandin E2 on blood capillaries to cause vasodilation and an increase in blood flow
-phagocytize foreign material
T/F
Most brain tumors in adults are found within neurons.
false
T/F
All PNS axons are covered in both neurilemma and myelin sheath.
false
T/F
The peripheral nervous system includes the brain and spinal cord.
false
During action poteintal, it never goes more than?
30mv
What are clusters of nerve cell bodies in the peripheral nervous system called?
ganglia
T/F
Regeneration of a cut axon is impossible in the PNS.
false
T/F
Each action potential is an all-or-none event.
true
_____ neurons are pseudounipolar and carry impulses toward the CNS.
sensory
_____ are released via exocytosis into the synaptic cleft.
neurotransmitter
G-proteins and _____ are the two main second-messenger molecules utilized in the body.
cAMP
Action potentials would be conducted most rapidly by
a. a 20mm diameter unmyelinated axon.
b. a 60mm diameter myelinated axon.
c. a 20mm diameter myelinated axon.
d. a 60mm diameter unmyelinated axon.
b.a 60mm diameter myelinated axon.
The neurotrophin that promotes the survival and growth of both sympathetic and sensory neurons in the developing fetal brain is
a. nerve growth factor.
b. brain-derived neurotrophic factor
c. neurotrphin-3
d. neurotrophin-4
e. glial-derived neurotrophic factor
a.nerve growth factor.
Retrograde transport:
a. moves toward the cell body from the axon.
b. uses dynein molecular motor proteins.
c. moves viruses and toxins.
d. a and b
e. b and c
f. a and c
g. a, b, and c
a, b, and c
Regeneration of CNS axons may be prevented by all of the following EXCEPT
a. glial scars.
b. death receptors.
c. neurotrophins.
d. NoGo proteins.
c.neurotrophins.
Which of the following is not a function of a neuron?
a. Releasing chemical regulators
b. Producing and conducting electrochemical impulses
c. Enabling perception of sensory stimuli, learning, memory, and control of muscles and glands
d. Responding to physical and chemical stimuli
e. Preventing axonal regeneration in the central nervous system
e.Preventing axonal regeneration in the central nervous system
The resting membrane potential of a neuron is _____mV.
-70
Blocking _____ channels (name the ion) would prevent neuron repolarization.
potassium
What is threshold in action potiental?
-55
Which neurons are responsible for stimulating or inhibiting contraction of smooth and cardiac muscle?
autonomic motor neurons
Blocking _____ channels (name the ion) would prevent neuron depolarization.
sodium
The gap of exposed axon in the myelin sheath is the
node of Ranvier.
The parasympathetic division of the autonomic nervous system
a. utilizes acetylcholine as a preganglionic neurotransmitter.
b. utilizes norepiniephrine as a postganglionic neurotransmitter.
c. includes the adrenal medulla.
d. has a relatively short preganglionic neuron.
a. utilizes acetylcholine as a preganglionic neurotransmitter.
T/F
Many autonomic visceral effector organs can function without nervous innervation.
true