Final Exam Flashcards
Normal plasma skim (filter) rate:
125ml/min
What triggers erythropoietin release?
epo is released in response to hypoxia of the inner parts of the kidney
Dominate controller of long term blood pressure
kidneys
Cholecalciferol
AKA Vitamine D
Explain the kidneys effect on vitamin D
The kidney puts 2 hydroxy groups on vitamin D which activate it. Activated vitamin D is known as 1,25 dihydroxycholecalciferol. It has its effect in the kidney and GI system. In the GI system it increases the rate at which calcium is absorbed. Elsewhere in the body is preserves calcium and prevent processes that use up calcium.
Major functions of the Kidney: (7)
1) Excretion of metabolic waste products
2) Excretion of foreign chemicals
3) Secretion, metabolism, and excretion of hormones
4) Regulation of acid-base balance
5) Gluconeogenesis
6) Control of arterial pressure
7) Regulation of water & electrolyte excretion
Dominate controller of long term blood pressure
Kidneys
Erythropoietin
primary regulator of hematocrit.
Increases RBC production in the bone marrow.
Gluconeogenesis
glucose synthesis of amino acids
perioperative glucose management
studies show better control of blood sugar = better outcome.
managed by giving insulin and colloids.
Metabolic waste products:
Urea
comes from the metabolism of proteins
Metabolic waste products:
uric acid
byproduct of metabolism of nucleic acid which are the building blocks of DNA
Metabolic waste products:
creatinine
released from skeletal muscle during normal metabolism
Metabolic waste products:
bilirubin
conjugated form of iron based products that come from a metabolism of hemoglobin.
How can the body get rid of protons?
only way is excretion through the kidneys
