Final Exam 2 Flashcards
What refers to the exchange of carbon dioxide and oxygen between systemic tissues and systemic capillaries?
Internal respiration
Label the following structures of the respiratory system: A. Nasal cavity, B. Nasal conchae, C. Nasopharynx, D. Oropharynx, E. Laryngopharynx, F. Larynx, G. Epiglottis, H. Trachea, I. Primary bronchi, J. Secondary & tertiary bronchi, K. Bronchioles, L. Terminal bronchioles, M. Respiratory bronchioles, N. Alveolar ducts, O. Alveolar sacs, P. Alveoli.
Respiratory system structures
What are the two types of mucous membranes lining the nasal cavity?
- Olfactory mucosa
- Respiratory mucosa
What type of epithelium lines the nasopharynx?
Pseudo stratified, ciliated, columnar epithelium
What type of epithelium is found in the oropharynx?
Stratified squamous epithelia
What is the structure of the larynx?
An intricate arrangement of nine cartilages, mostly hyaline, with a stratified squamous epithelium above and pseudo-stratified ciliated columnar epithelium below
What are the three layers of the tracheal walls?
- Mucosa
- Submucosa
- Adventitia
What is the function of the respiratory membrane?
Exchange of gases between the alveoli and the pulmonary capillaries
The alveoli are well suited to gas exchange because of:
- Their combined surface is huge
- Their walls are thin
- The presence of surfactant
Surfactant helps to prevent the alveoli from collapsing by _______.
interfering with the cohesiveness of water molecules, thereby reducing the surface tension of alveolar fluid
Describe the process of ventilation (breathing).
Ventilation occurs by changing the volume of the thorax, which alters lung volume and pressure, causing air to move in or out.
Air moves into the lungs (inhalation) when the pressure inside the lungs is ________.
less than the pressure in the atmosphere
Contraction of the diaphragm causes thoracic volume to:
Increase
How do respiratory gases diffuse across membranes?
Partial pressure gradients of O2 and CO2 drive diffusion across the respiratory membrane.
By what two mechanisms is O2 carried in the blood?
- Dissolved in the plasma (1.5%)
- Carried by hemoglobin (98.5%)
By what three mechanisms is CO2 carried in the blood?
- Dissolved in the plasma (7-10%)
- Carried in hemoglobin (20%)
- Carried as Bicarbonate ions (HCO3-) (~70%)
Which of the following is NOT true about how oxygen and carbon dioxide are carried in the blood?
F. All are true statements
What is the biggest determinant in dictating how respiratory gases move across membranes?
Partial pressure of the respiratory gases
Label the following layers of the alimentary canal: A. Mucosa, B. Submucosa, C. Muscularis externa, D. Serosa.
Layers of the alimentary canal
Name the mucosal epithelial tissue type associated with the mouth.
Stratified squamous epithelium, keratinized in some places
Identify the following structures of the stomach: A. cardiac region, B. Fundus, C. Body, D. Pylorus, E. Pyloric sphincter/valve, F. Rugae.
Stomach structures
What are the modifications seen in the muscularis externa of the stomach?
It has an oblique muscle layer in addition to circular and longitudinal muscle layers.
What hormone controls the secretion of other stomach secretions?
Gastrin
Identify the following regions of the small intestine: A. Duodenum, B. Jejunum, C. Ileum.
Regions of the small intestine
Describe the three major modifications of the small intestinal wall.
- Circular folds
- Villi
- Microvilli (brush border)
What is the role of the simple columnar absorptive cells found in the epithelial villus mucosa of the small intestine?
To absorb nutrients and electrolytes from digested food.
What is the main digestive role of the liver?
To produce bile
What is the function of bile?
To help emulsify fats for easier digestion
What is the major function of pancreatic juice?
Contains enzymes that breakdown all categories of food
Describe the gastroileum reflex.
Caused by stomach activity and gastrin release, increasing ileum segmentation to push food residues into the large intestine.
What is the role of the mucosa in the large intestine?
To secrete mucus that helps the passage of food residues and protects the large intestine wall.
True or False: Most nutrients are absorbed through the simple columnar absorptive cells of the stomach.
False
True or False: Gastrin is a digestive hormone that is primarily responsible for the stimulation of other stomach secretions.
True
True or False: Food enters the stomach via the pylorus and exits via the fundus.
False
True or False: The major function of bile is to break down fats to aid in their solubilization and absorption.
True
True or False: The circular folds of the small intestine enhance absorption by causing the chyme to spiral.
True
What is the major function of bile?
To break down fats to aid in their solubilization and absorption.
True or False: All chemical and mechanical phases of digestion from the mouth through the small intestine are directed toward changing food into forms that can pass through the epithelial cells.
True
Which of the following statements about the stomach is false?
B. The mucosa of the stomach is primarily simple stratified epithelial cells joined by tight junctions.
What modifications enhance the absorptive effectiveness of the small intestine mucosa?
Numerous mucus secreting goblet cells, circular folds, villi, and microvilli.
List the functions of the kidneys.
- Regulating the total volume of water in the body
- Regulating the ion concentration of the extracellular fluids
- Ensuring long-term acid-base balance
- Excreting metabolic wastes and foreign substances
- Producing erythropoietin and renin
Identify the following structures of the kidneys: A.
Cortex
Identify the following structures of the kidneys: B.
Medulla
Identify the following structures of the kidneys: C.
Pyramids
Identify the following structures of the kidneys: D.
Columns
Identify the following structures of the kidneys: E.
Pelvis
Identify the following structures of the kidneys: F.
Calyces (Calyx)
Identify and describe the structures of a nephron: A.
Glomerulus (incl. glomerular capsule, afferent & efferent arterioles)
Identify and describe the structures of a nephron: B.
Proximal convoluted tubule
Identify and describe the structures of a nephron: C.
Nephron loop
Identify and describe the structures of a nephron: D.
Distal convoluted tubule
Identify and describe the structures of a nephron: E.
Collecting duct
Where are the peritubular capillaries or Vasa Recta found?
Surrounding the renal tubules
Describe the juxtaglomerular complex.
The region where the most distal portion of the ascending limb of the nephron loop lies against the afferent arteriole.
What are macula densa cells?
Chemoreceptors that monitor the NaCl content of the filtrate.
What are granular cells?
Enlarged smooth muscle cells that sense blood pressure in the afferent arteriole.
What are extraglomerular mesangial cells?
Cells that may pass regulatory signals between macula densa and granular cells.
What are the components of the filtration membrane?
- Fenestrated glomerular capillaries
- Podocytes of the glomerular capsule
- Fused basement membrane
List the three steps of urine formation.
- Glomerular filtration
- Tubular reabsorption
- Tubular secretion
Describe the process of glomerular filtration.
A passive process where hydrostatic pressure forces fluids and solutes through the filtration membrane.
What substances get through during glomerular filtration?
Small molecules; proteins and blood cells remain in the capillaries.
What is the primary site for tubular reabsorption?
Proximal convoluted tubule (PCT)
What substances are generally reabsorbed during tubular reabsorption?
- All organic molecules (glucose, amino acids, vitamins)
- Water (65%)
- Sodium (65%)
- Electrolytes (Na+, K+, Cl-, Ca2+)
Describe tubular secretion.
Movement of substances from the blood into the filtrate.
What substances are generally secreted during tubular secretion?
- H+
- K+
- NH4+
- Creatinine
- HCO3
- Certain organic acids and bases
How do the kidneys help maintain body fluid osmolality?
By altering the concentration of the urine produced.
What role does ADH play in urine concentration?
Increases the amount of water reabsorbed by the distal convoluted tubules and collecting ducts.
Which of the following is NOT a function of the urinary system?
D. Eliminates solid, undigested wastes and excretes carbon dioxide, water, salts, and heat.
Identify the function of the ureters.
Transport urine from the kidneys to the bladder.
Identify the function of the bladder.
Stores urine until it is expelled from the body.
Identify the function of the urethra.
Conducts urine out of the body.
Identify the function of the trigone.
Smooth triangular area in the bladder where ureters enter and urethra exits.
Identify the function of the detrusor muscle.
Muscle that contracts to expel urine from the bladder.
Identify the function of the internal urethral sphincter.
Controls the release of urine from the bladder.
Identify the function of the external urethral sphincter.
Controls voluntary release of urine.
True or False: The path urine takes after it is formed until it leaves the body is the urethra, urinary bladder, and finally the ureter.
False
True or False: Glomerular filtration is a passive process.
True
True or False: In the absence of hormones, the distal tubule and collecting ducts are relatively impermeable to water.
True
True or False: The urethra contains an internal sphincter of smooth muscle.
True
True or False: Antidiuretic hormone (ADH) is the most important regulator of urine concentration and volume.
True
The glomerulus differs from other capillaries in the body in that it ________.
C. is drained by an efferent arteriole.
Which of the following does not describe the juxtaglomerular complex?
D. Its macula densa cells produce aldosterone.
The filtration membrane includes all except ________.
C. renal fascia
The macula densa cells respond to ________.
D. changes in solute content of the filtrate.
The fluid in the glomerular capsule (filtrate) is similar to plasma except that it does not contain ________.
D. plasma proteins
Which of the following statements about glomerular filtration and the filtration membrane is false?
C. Molecules such as water, glucose and proteins pass easily through the filtration membrane.