Final: Antimicrobials

Question 1

cocci

Answer 1

sphere shape bacteria

Question 2

bacilli

Answer 2

rod shaped bacteria

Question 3

spirochetes

Answer 3

Tightly coiled bacteria

Question 4

Three major mechanisms of amr

Answer 4

Alteration in drug target

Production of inactivating enzymes

Decreased uptake of antibiotic

Question 5

Penicillins
Cephalosporins
Monobactams
Carbapenems

Answer 5

antibiotic
Beta Lactams

Cell wall inhibitors

prevent peptide cross links

Question 6

Aminoglycosides
Macrolides

Answer 6

Protein synthesis inhibitors

Question 7

Folate synthesis inhibitors (trimethoprim-sulfamethoxazole)

Fluoroquinolones

Answer 7

antibiotic

Nucleic acid inhibitors

Question 8

Isoniazid
Pyrazinamide

Answer 8

antibiotic

Anti-mycobacterials

Question 9

vancomycin

Answer 9

cell wall inhibitor

prevents transfer of sugar-pentapeptide

Question 10

Gentamicin, tobramycin, amikacin, neomycin, streptomycin

Answer 10

Aminoglycosides

inhibit 30s ribosome subunit

gram-

Question 11

azithromycin, clarithromycin, erythromycin

Answer 11

Macrolides

inhibit 50s ribosome subunit

gram+

Question 12

Sulfonamides
Trimethoprim - Sulfamethoxazole

Answer 12

folate synthesis antag

Question 13

ciprofloxacin, moxifloxacin, levofloxacin

Answer 13

Fluoroquinolones

inhibit dna gyrase and type 4 topoisomerase

Question 14

Isoniazid

Answer 14

treatment of mycobacteria

inhibits synthesis of mycolic acids

Question 15

Pyrazinamide

Answer 15

treatment of mycobacteria