FHDT pharmacology Flashcards
What a drug does to my body
It includes
- drug action
- receptor theory
- qualntitative aspects of drug addiction
- dose-response curves
Pharmacodynamics
What my body does to a drug
It includes:
- Absorption
- Distribution
- Metabolism
- Elimination
- Bioavalibility and bioequivalence
- Fluid compartments
- Phase reactions
Pharmacokinetics
- What kind of drug is it? What class of drug is it? What group of drug is it
- Mechanism of action of the drug (site of action of drug)
- Clinical applications (uses). I need to know this is the disease
- No drug is w/o any side effects, I need to know adverse effects of drug
- Drug-drug interactions. If pt. gets 2 dugs, the body may have something that might alter the drug. I need to know the counterindications.
Golden rule of pharmacology:
It’s the study of what drugs do and how they do it
pharmacology
It’s defined as any synthetic or natural chemical substance used in the treatment, prevention, and diagnosis of disease
drug
- class/group of drug
- mechanism of action of drug
- therapeutic applications of drug
- adverse and toxic effects of drug
- drug-drug interactions
Study guide for pharmacology (know these 5 things for every drug we’re required to know)
It’s how the drug works, usually by enhancing or inhibiting cell function (mechanism)
action
it’s consequence of drug action on the body (benefit/result)
effect
It’s action that occurs at therapeutic dose levels
side effects
it’s action that occurs when blood concentration is above therapeutic level
toxic effect
drug that produces en effect comparable to endogenous ligand
agonist
drug that blocks or inhibits action of an endogenous compound or another drug
antagonist
Measure of amount of drug required for effect (ED50)
potency
Maximum effect obtained with drug
efficacy
Effect of incremental increase in dose
Slope: