Fever and infectious diseases in children Flashcards
How do you work up fever in an infant < 21 days old?
- admit for fever
- CBC with diff
- blood cultures
- UA and Urine culture
- LP for CSF studies and culture
- CXR if resp sxs
- Stool studies if diarrhea present
What are the IV antibiotic regimens you could use in infant < 21 days with fever?
Which IV Abx should you avoid?
- Amp + gent
- Amp + cefotaxime
+/- acyclovir
AVOID rocephin if < 1 mo –> kernicterus risk
How do you work up infant 21-90 days old who have fever and are ill appearing?
- treat them the same as a < 21 day old if poor appearance, breathing, or circulation
What is the step by step approach for working up a 21-90 day old who has fever but appears up
UA for leukocytes
If negative get procalcitonin
if negative et CRP and CBC –> if CRP < 20 or ANC < 10K then there is low risk for invasive bacterial infection
What workup do you do for first simple febrile seizure in kids?
No workup
What is the most common serious bacterial infection in children?
UTI –> look for it when no other obvious sources
Antibiotic regimen to treat UTI in kids
Treat when > 50K CFU
- Abx: Cephalosporin or bactrim for 7-14 days
When a child has a UTI, when is imaging warranted and which study should you get?
Renal US - if first febrile UTI < 2 yo OR - recurrent UTIs (more than 1) Follow with voiding cystourethrogram (VCUG) if... - US reveals hydronephrosis/scarring OR - recurrent febrile UTIs (more than 1)
What do you do for the following scores on the Centor criteria for group A strep pharyngitis?
0-1
2-3
4-5
0-1 –> no testing or treatment
2-3 –> test with rapid antigen detection. Culture if negative in kids. Treat if positive
4-5 –> no testing, just treat
Treatment for strep pharyngitis
PCN/amoxicillin for 10 days
macrolide or clinda if PCN allergic
Prevents rheumatic fever but not glomerular nephritis
Should I test kids of all ages for Group A beta hemolytic strep?
No
IDSA 2012 guidelines indicate that GABHS infection is uncommon in children < 3 yo and recommend AGAINST testing them
Treatment for Epiglottitis
- Airway management
- Abx: Cephalosporin +/- clinda
- steroids and recemic epi are NOT used
Treatment of viral URIs
- Buckwheat honey ***
- Umcka coldcare
- Nasal saline irrigation
- zinc
- Vaporub –> don’t use < 2 yo –> airway inflammation
OTC cough/cold meds NOT recommended, particularly under age of 4
Management of lymphadenopathy in children
- watchful waiting up to 4 weeks (in absence of red flags)
- oral Abx can be considered if infalmmation evident
- If persistent or red flag sxs –> CBC/smear, ESR, CXR
- imaging: US if < 24 mo, CT if > 14 yo
Treatment of herpetic gingivostomatitis
oral acyclovir