Female Reproductive

Question 1

Most common cause of PID?

Answer 1

Neisseria gonorrhea

Question 2

Condyloma accuminatum

Answer 2

HPV

Question 3

MC venereal disease

Answer 3

HPV

Question 4

Most common causes of bartholin cysts (3)

Answer 4

1. Staph
2. Chlamydia
3. Anaerobes

Question 5

Abnormal growth of vulvar skin with white plaques (hyperkatosis), atrophy/thinning of the skin due to low estrogen*

Answer 5

Lichen Sclerosis

Question 6

Slow growing, wart-like slightly raised mucosal lesion, squamous cell carcinoma. Preneoplastic lesions (Bowen’s disease and leeukoplakia) that lead to invasive cancer

Answer 6

Carcinoma of the vulva

Question 7

Which cancer is rare tumor of the vagina in young women caused by exposure to diethyl-stilbesterol (DES)

Answer 7

Clear Cell Adenocarcinoma

Question 8

Rare vaginal tumor in children from connective tissue, striated muscle. Polypoiid masses extending from the introitus of vagina

Answer 8

Embryonal Rhabdomyosarcoma (Sarcoma Botyoides)

Question 9

Metaplasia of the squamocolumnar junction

Answer 9

Mucinous columnar to stratified squamous epithelium

Question 10

Cause of cervix inflammation

Answer 10

Staph, strept most commonly

Question 11

Which carcinoma of the female reproductive tract is characterized by intense cell proliferation, undifferentiated and is associated with HPV 16, 18

Answer 11

Cervical cancer

Question 12

Which HPVs are most associated with cancer?

Answer 12

16, 18

Question 13

Which HPVs are associated with benign lesions?

Answer 13

6, 11

Question 14

Name the 2 important macroscopic cervical cancer findings?

Answer 14

1. Mosaic pattern
2. Tortuosity of vessels

-smooth shiny crater-like ulceration

Question 15

What is the most common cause of death for someone with stage 4 cervical cancer?

Answer 15

progressive renal failure due to obstruction

Question 16

Clinical features of cervical cancer? (2)

Answer 16

1. vaginal bleeding after intercourse

2. Vaginal discharge becomes increasingly purulent and foul-smelling

Question 17

What are chocolate cysts and what are they associated with?

Answer 17

Endometriosis, large cystic lesions filled with brown-red viscous fluid from decomposed blood

Question 18

What is the most common uterine tumor?

Answer 18

Leiomyomas (“fibroid”)

Question 19

What population is at higher risk for fibroids?

Answer 19

blacks

Question 20

Which fibroid (leiomyoma) is most commonly associated with infertility?

Answer 20

Submucosa - interfere with egg implantation

Question 21

Where is the most common location for endometrial polyps?

Answer 21

Fundus

Question 22

What disease shows hypersensitive growth to estrogen and unresponsive to progesterone?

Answer 22

endometrial polyps

Question 23

Most common malignant tumor of female genital tract?

Answer 23

Endometrial Adenocarcinoma

• epithelial cells lining endometrial glands
• friable, prone to bleeding

Question 24

Thick, tough, pearly white capsule of ovary

• Amenorrhea
• Hirsutism
• Obesity
• Continous abnormal stimulation of ovary by FSH and LH–>produce androgens

Answer 24

Polycystic Ovarian Syndrome

Question 25

2nd most common GYN cancer | 1st most deaths of GYN cancer

Answer 25

Ovarian

Question 26

Most common ovarian cancer

Answer 26

tumors of surface (germinal) epithelium -of which, Serous are the most common

Question 27

Name the 2 types of surface epithelium ovarian neoplasms

Answer 27

1. Serous | 2. Mucinous

Question 28

Mucinous ovarian tumor

Answer 28

filled with thick, yellowish-clear jelly-like materrial * *Pseudomyxoma peritonei - mimic endocervical epithelium

Question 29

Which ovarian tumor is solid and made of dense fibrous stroma from transitional epithelium

Answer 29

Brenner

Question 30

What is the most common ovarian tumor in young women?

Answer 30

Benign cystic teratoma | -hary skin, teeth, bone, cartilage, sweat glands

Question 31

What is the counterpart to the male seminoma

Answer 31

Dysgerminoma

Question 32

- Counterpart to the Yolk sac tumor in male testes | - Rich in alpha feto protein (AFP)

Answer 32

Endodermal sinus tumor

Question 33

Which germ cell tumor is rare, aggressive, highly lethal and releases hCG?

Answer 33

Choricarcinoma

Question 34

Name the 4 Germ cell tumors

Answer 34

1. Benign cystic teratoma 2. Dysgerminoma 3. Endodermal Sinus tumor 4. Choricarcinoma

Question 35

Name the 4 epithelial ovarian tumors

Answer 35

1. Serous 2. Mucinous 3. Endometroid (solid) 4. Brenner (solid)

Question 36

What is the most common predisposing factor for ectopic pregnancy

Answer 36

chronic salpingitis

Question 37

Most common location of ectopic pregnancy

Answer 37

fallopian tube

Question 38

What is absence of chorionic villi associated with?

Answer 38

ectopic pregnancy

Question 39

- Snowstorm pattern and no fetal heartbeat (Ultrasound) - High serum and urine levels of hCG - Placenta grape-like fluid filled clear vesicles

Answer 39

Hydatidiform mole

Question 40

What's the most common type of mole?

Answer 40

Complete mole

Question 41

What is associated with two sets of paternal chromosomes, no maternal chromosomes for a total of 46 chromosomes (androgenesis)

Answer 41

Complete mole

Question 42

What trophoblastic disease (proliferative disease) is associated with 69 chromosomes (one from mom, 2 from dad? -Parts of embryo are found

Answer 42

Incomplete mole

Question 43

Which trophoblastic disease is highly malignant, highly invasive (invades veins and goes to liver, lung and brain) and will secrete hCG?

Answer 43

Choriocarcinoma

Question 44

Treatment for choriocarcinoma?

Answer 44

Methotrexate (chemotherapy)