Female Reproductive Flashcards

0
Q

What is under the topmost epithelium of the ovaries

A

Tunica albuginea

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1
Q

The ovaries are covered by what epithelium

A

Simple squamous or cuboidal

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2
Q

What part of the ovary has the follicles

A

Cortex

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3
Q

What part of the ovary has the vessels of the ovary

A

Medulla

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4
Q

Cells that start in yolk sac and move to gonads (ovary) transform I to what first

A

Oogonia

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5
Q

Oogonia transform Into what

A

Primary oocytes

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6
Q

What meiotic stage are primary oocytes in by 7th month

A

Diplotene stage of first prophase of meiosis 1

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7
Q

What is an ovarian follicle

A

Oocyte surrounded by one or more layers of follicular cells

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8
Q

What stimulates follicular growth

A

FSH

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9
Q

Once a primordial follicle forms a single layer of cuboid follicular cells by mitosis, the follicle is now a __________

A

Unilaminar primary follicle

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10
Q

How does communication occur in the granulosa layer of the follicle

A

Gap junctions

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11
Q

Where does the zona pellucida come from

A

Oocyte and follicular cells

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12
Q

A follicle with a zona pellucida, granulosa layer is what type of follicle

A

Multilaminar primary follicle

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13
Q

A follicle with a cumulus oophorus, corona radiata, and an Antrum is a _____________ follicle

A

Secondary or antral

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14
Q

What is theca interna responsible for

A

Synthesizing androstenedione

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15
Q

What is the theca externa responsible for

A

Layers of fibroblasts

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16
Q

What is the path of androstenedione

A

It goes to the granulosa layer
It’s converted to estrogen with FSH present
Estrogen goes to stroma and rest of body

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17
Q

What is the most mature follicle type

A

Graafian follicle

Only one reaches this

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18
Q

When is follicular atresia most intense

A

At birth
Puberty
Pregnancy

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19
Q

What surge of hormone causes ovulation

A

LH (stimulated by estrogen)

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20
Q

What occurs to the Oocyte immediately prior to ovulation

A

Meiosis 1 is completed and Oocyte stops in metaphase of meiosis 2

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21
Q

When the follicle ruptures, what is the Oocyte still enclosed in

A

Zona pellucida
Corona radiata
Follicular fluid

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22
Q

What cells make up the Corpus luteum

A

Theca interna cells

Granulosa cells

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23
Q

What do the granulosa cells of the corpus luteum do and turn into

A

Granulosa lutein cells

Secrete steroids

24
What do the theca interna cells become in the corpus luteum
Theca lutein cells
25
LH causes the cells of the corpus luteum to secrete what
Progesterone and estrogen
26
What is the corpus alibicans
Scar left from corpus luteum that degenerated
27
What happens to the corpus luteum if pregnancy occurs
It starts secreting HcG from trophoblastic cells | This stimulates progesterone
28
What are the three layers of uterine tubes
Mucosa Muscularis Serosa
29
What type of epithelium is the mucosa of the uterine tube
Simple columnar epithelium with Ciliated and secretory cells
30
What two important things are in the uterine tube secretions
Nutrients for Oocyte | Substances for capacitation of sperm
31
Penetration of the Oocyte by sperm triggers what
Completion of the second meiotic division
32
What are the three layers of the uterus
Serosa Myometrium Endometrium
33
What happens to the myometriuim during pregnancy
Undergoes hyperplasia and hypertrophy | Smooth muscle cells Synthesize collagen
34
Endometrium has what two types of cells
Ciliated | Secretory simple columnar
35
What type of collagen is endometrium
Type 3
36
What are the two layers of endometrium
Stratum functionale | Stratum basale
37
How does the myometrium get blood
Uterine a. > arcuate a.
38
How does the stratum basale get blood
Uterine a. > arcuate a. > radial a. > straight a. Branches
39
What branches off the radial artery are important for the stratum functionale
Spiral a. Branches
40
What are the three phases of the menstrual cycle
Menstrual phase (actual flow) Proliferative phase Secretory phase
41
What is happening during the proliferative phase
Follicles are growing and producing estrogen | Estrogen stimulates cell proliferation in the endometrium
42
What is happening during the secretory phase
Progesterone from the corpus luteum causes changes in stratum functionale
43
What initiates the menstrual phase
Rapid decline in progesterone levels when corpus luteum stops functioning
44
Once implantation occurs, the endometrium becomes what
Decidua with decidual cells
45
What are the three types of decidua
``` Decidua basalis (between baby and myometrium) Decidua capsularis (bw baby and lumen) Decidua parietalis (remainder) ```
46
Where is the site of dysplastic changes in the cervix
Transformation zone
47
Where is the transformation zone in the cervix
Just outside the cervical os in reproductive women | In the cervical canal after menopause and before puberty
48
What is the transformation zone
An abrupt change between endocervix (columnar) and ectocervix (stratified squamous )
49
What are the three layers of the vaginal wall
Mucosal layer | Muscular layer adventitia layer
50
During the follicular phase, what do the cells of the vagina do
Secrete glycogen
51
What type of epithelium is in the lactiferous sinus
Two layered cuboidal
52
What type of epithelium is in the lactiferous duct (opens into nipple)
Stratified squamous epithelium
53
What type of epithelium is in rest/majority of lactiferous duct system
Simple columnar/ cuboidal
54
What role does estrogen have in mammary glands and pregnancy
Duct growth
55
What role does progesterone have on mammary glands and pregnancy
Alveolar growth
56
How are protein components released during lactation
Merocrine secretion
57
How are lipid components released during lactation
Apocrine secretion
58
How is colostrum different than milk
High IgA content | More protein and less carbs and fats