Fallopian/Ovarian disorders/infections Flashcards
The most common disorders affecting the fallopian tube are
The most common disorders affecting the fallopian tube are infections and associated inflammatory conditions (salpingitis) > followed by ectopic (tubal) pregnancy and endometriosis.
Tubo-ovarian abscess
benign cyst in an ovary. This is probably a follicular cyst. Occasionally such cysts may reach several centimeters in size and, if they rupture, can cause abdominal pain.
Tubo-ovarian abscess, gross
This condition followed Neisseria gonorrhoeae infection, although other organisms, including Chlamydia trachomatis, can cause this disease.
Gonorrhea leads to multiple complications in the female genital tract, including acute inflammation with abscess formation and chronic inflammation with tubal scarring (and a greater likelihood of ectopic pregnancy) and PID.
There is no clear boundary here between tube and ovary, and this dilated ovary on sectioning is filled with purulent materia
- tubal epithelium surrounded and infiltrated by numerous neutrophils. N. gonorrhoeae.
- The next most likely causative organism for this acute suppurative process is C. trachomatis.
- Multiple pyogenic bacterial species may be present with acute salpingitis that evolves to PID, including enteric bacteria, staphylococci, streptococci, and clostridia.
- Clinical findings include pelvic pain and fever. Infertility may result from this process. Laboratory findings include leukocytosis with a left shift.
Clinical findings include pelvic pain and fever.
Infertility may result from this process.
Laboratory findings include leukocytosis with a left shift.
suppurative salpingitis, tubo-avarian abscess, N gonorrhea
hydrosalpinx
A hydrosalpinx is a distally blocked fallopian tube filled with serous or clear fluid. The blocked tube may become substantially distended giving the tube a characteristic sausage-like or retort-like shape.
oophoritis
uncommon, usually autoimmune etiology, may lead to infertility
follicule cyst may cause pain and be palpable when…
> 2/2.5cm then called
normal cyst on the left, abnormal on the right
a hemorrhagic corpus luteum. Note the dark red-black hemorrhagic region surrounded by a thin rim of yellow corpus luteum.
benign theca lutein cyst in an ovary.
Note the luteinized cells forming the inner cyst lining at the left, with adjacent surrounding theca cells.
These cysts are rarely more than a few centimeters in diameter.
PCOS
estrogen review
E1 =
E1 = estrone–> menopausal estrogen produced by aromatization of androstenedione in peripheral fatty tissue. Less potent than E2 estradiol
estrogen review
E2 =
E2 = estradiol predominates in reproductive years.
Most potent estrogen produced by aromatization of testosterone in Graafian follicle
estrogen review
E3 =
E3 = estriol placental estrogen: originates in fetal adrenal gland as DHEA and converted in placenta.
Least potent.