cervical cancer/neoplasia

Question 1

average age for cervical cell carcinoma

Answer 1

45

Question 2

80% of cervical carcinomas are

Answer 2

squamous cell carcinomas

Question 3

characterized by proliferation of glandular epithelium composed of malignant endocervical cells with large hyperchromatic nuclei and relatively mucin depleted cytoplasm

Answer 3

adenocarcinoma of the cervix

Question 4

a neoplasia with a high viral profliferation and low cellular proliferation

Answer 4

LSIL

Question 5

a neoplasm with a low viral count/proliferation and a high cellular proliferation

Answer 5

HSIL

Question 6

LSIL –> carcinoma?

Answer 6

no. most cases regress spontaneously.

Question 7

HSILs –> carcinoma?

Answer 7

considered high risk for progression to carcinoma

Question 8

upper cells will express markers Ki-67

Answer 8

LSIL morphology biomarker

Question 9

overexpression of p16

Answer 9

LSIL morphology biomarker

Question 10

HPV and LSIL/HSIL

Answer 10

100% HSIL; 80% LSIL (20% de novo)

Question 11

nests/tongues of malignant cell epithelium, keratinizing and non-keratinizing

Answer 11

f