Factors Flashcards
What is the site of formation of the coagulation factors?
Liver
List the Vitamin K dependent factors
II, VII, IX, and X
Factor I
Fibrinogen
Clot formation
Factor Ia
Fibrin (monomer)
Factor II
Prothrombin
Activation of factors I, V, VII, VIII, XI, XIII, Protein C, and platelets
Factor IIa
Thrombin
Factor III
Tissue factor III
Cofactor of VIIa
Factor IV
Calcium (Ca++)
Role in binding of phospholipid coagulation factors
Factor V
Labile Factor
Cofactor of X – prothrombinase complex
Activated by Thrombin (IIa)
Targets Protein C
Factor VII
Proconvertin or Stable Factor
Enables factors IX and X
Factor VIII
von Willebrand Factor Complex
Cofactor of IX complex
Activated by Thrombin (IIa)
Targets Protein C
Factor IX
Christmas Factor
Forms the complex with VIII; Enables factor X
Factor X
Stuart-Prower Factor
Forms the prothrombinase complex together with Factor V, which will activate Factor II
Factor XI
Activates factor IX
Factor XII
Hageman Factor
Enables factors XI, VII, and Prekallikrein
